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BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
Herbert K, Binet R, Lambert JP, Louphrasitthiphol P, Kalkavan H, Sesma-Sanz L, Robles-Espinoza CD, Sarkar S, Suer E, Andrews S, Chauhan J, Roberts ND, Middleton MR, Gingras AC, Masson JY, Larue L, Falletta P, Goding CR. Herbert K, et al. Among authors: sarkar s. Genes Dev. 2019 Mar 1;33(5-6):310-332. doi: 10.1101/gad.314633.118. Epub 2019 Feb 25. Genes Dev. 2019. PMID: 30804224 Free PMC article.
DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey T, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: sarkar s. bioRxiv [Preprint]. 2023 Apr 21:2023.04.21.537819. doi: 10.1101/2023.04.21.537819. bioRxiv. 2023. PMID: 37131595 Free PMC article. Preprint.
DNA damage remodels the MITF interactome to increase melanoma genomic instability.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey TC, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: sarkar s. Genes Dev. 2024 Feb 13;38(1-2):70-94. doi: 10.1101/gad.350740.123. Genes Dev. 2024. PMID: 38316520 Free PMC article.
Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
Hazrati A, Ramis-Castelltort M, Sarkar S, Barber LJ, Schofield CJ, Hartley JA, McHugh PJ. Hazrati A, et al. Among authors: sarkar s. DNA Repair (Amst). 2008 Feb 1;7(2):230-8. doi: 10.1016/j.dnarep.2007.09.013. Epub 2007 Nov 19. DNA Repair (Amst). 2008. PMID: 18006388
The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast.
Blaikley EJ, Tinline-Purvis H, Kasparek TR, Marguerat S, Sarkar S, Hulme L, Hussey S, Wee BY, Deegan RS, Walker CA, Pai CC, Bähler J, Nakagawa T, Humphrey TC. Blaikley EJ, et al. Among authors: sarkar s. Nucleic Acids Res. 2014 May;42(9):5644-56. doi: 10.1093/nar/gku190. Epub 2014 Mar 12. Nucleic Acids Res. 2014. PMID: 24623809 Free PMC article.
6,423 results