Ahmad R - Search Results

1

Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives.

El-Sayed NNE, Almaneai NM, Ben Bacha A, Al-Obeed O, Ahmad R, Abdulla M, Alafeefy AM. El-Sayed NNE, et al. Among authors: ahmad r. J Enzyme Inhib Med Chem. 2019 Dec;34(1):672-683. doi: 10.1080/14756366.2019.1574780. J Enzyme Inhib Med Chem. 2019. PMID: 30821525 Free PMC article.

2

Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.

Eldehna WM, Abo-Ashour MF, Al-Warhi T, Al-Rashood ST, Alharbi A, Ayyad RR, Al-Khayal K, Abdulla M, Abdel-Aziz HA, Ahmad R, El-Haggar R. Eldehna WM, et al. Among authors: ahmad r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):319-328. doi: 10.1080/14756366.2020.1862100. J Enzyme Inhib Med Chem. 2021. PMID: 33345633 Free PMC article.

3

Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.

Alafeefy AM, Ahmad R, Abdulla M, Eldehna WM, Al-Tamimi AM, Abdel-Aziz HA, Al-Obaid O, Carta F, Al-Kahtani AA, Supuran CT. Alafeefy AM, et al. Among authors: ahmad r. Eur J Med Chem. 2016 Feb 15;109:247-53. doi: 10.1016/j.ejmech.2016.01.001. Epub 2016 Jan 6. Eur J Med Chem. 2016. PMID: 26774930

4

In vitro evaluation of cytotoxicity, possible alteration of apoptotic regulatory proteins, and antibacterial activity of synthesized copper oxide nanoparticles.

Khan S, Ansari AA, Khan AA, Abdulla M, Al-Obaid O, Ahmad R. Khan S, et al. Among authors: ahmad r. Colloids Surf B Biointerfaces. 2017 May 1;153:320-326. doi: 10.1016/j.colsurfb.2017.03.005. Epub 2017 Mar 6. Colloids Surf B Biointerfaces. 2017. PMID: 28285257

5

Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2-STAT3 pathway.

Al-Obeed O, Vaali-Mohammed MA, Eldehna WM, Al-Khayal K, Mahmood A, Abdel-Aziz HA, Zubaidi A, Alafeefy A, Abdulla M, Ahmad R. Al-Obeed O, et al. Among authors: ahmad r. Onco Targets Ther. 2018 Jun 5;11:3313-3322. doi: 10.2147/OTT.S148108. eCollection 2018. Onco Targets Ther. 2018. PMID: 29892198 Free PMC article.

6

Induction of ROS‑mediated cell death and activation of the JNK pathway by a sulfonamide derivative.

Ahmad R, Vaali-Mohammed MA, Elwatidy M, Al-Obeed O, Al-Khayal K, Eldehna WM, Abdel-Aziz HA, Alafeefy A, Abdulla M. Ahmad R, et al. Int J Mol Med. 2019 Oct;44(4):1552-1562. doi: 10.3892/ijmm.2019.4284. Epub 2019 Jul 23. Int J Mol Med. 2019. PMID: 31364730

7

Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration.

Al-Khayal K, Alafeefy A, Vaali-Mohammed MA, Mahmood A, Zubaidi A, Al-Obeed O, Khan Z, Abdulla M, Ahmad R. Al-Khayal K, et al. Among authors: ahmad r. BMC Cancer. 2017 Jan 3;17(1):4. doi: 10.1186/s12885-016-3005-7. BMC Cancer. 2017. PMID: 28049506 Free PMC article.

8

A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway.

Al-Khayal K, Vaali-Mohammed MA, Elwatidy M, Bin Traiki T, Al-Obeed O, Azam M, Khan Z, Abdulla M, Ahmad R. Al-Khayal K, et al. Among authors: ahmad r. BMC Cancer. 2020 Jul 23;20(1):685. doi: 10.1186/s12885-020-07165-w. BMC Cancer. 2020. PMID: 32703189 Free PMC article.

9

Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β‑catenin and increases irinotecan sensitivity in colorectal cancer.

Abdulla M, Traiki TB, Vaali-Mohammed MA, El-Wetidy MS, Alhassan N, Al-Khayal K, Zubaidi A, Al-Obeed O, Ahmad R. Abdulla M, et al. Among authors: ahmad r. Int J Oncol. 2022 Mar;60(3):22. doi: 10.3892/ijo.2022.5312. Epub 2022 Jan 21. Int J Oncol. 2022. PMID: 35059735 Free PMC article.

10

Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients.

Al-Khayal K, Abdulla M, Al-Obeed O, Al Kattan W, Zubaidi A, Vaali-Mohammed MA, Alsheikh A, Ahmad R. Al-Khayal K, et al. Among authors: ahmad r. Oncol Rep. 2016 Mar;35(3):1281-6. doi: 10.3892/or.2015.4494. Epub 2015 Dec 17. Oncol Rep. 2016. PMID: 26675982 Free PMC article.

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