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Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.
Claus J, Patel G, Autore F, Colomba A, Weitsman G, Soliman TN, Roberts S, Zanetti-Domingues LC, Hirsch M, Collu F, George R, Ortiz-Zapater E, Barber PR, Vojnovic B, Yarden Y, Martin-Fernandez ML, Cameron A, Fraternali F, Ng T, Parker PJ. Claus J, et al. Among authors: george r. Elife. 2018 May 1;7:e32271. doi: 10.7554/eLife.32271. Elife. 2018. PMID: 29712619 Free PMC article.
α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster.
Gordon O, Henry CM, Srinivasan N, Ahrens S, Franz A, Deddouche S, Chakravarty P, Phillips D, George R, Kjaer S, Frith D, Snijders AP, Valente RS, Simoes da Silva CJ, Teixeira L, Thompson B, Dionne MS, Wood W, Reis e Sousa C. Gordon O, et al. Among authors: george r. Elife. 2018 Sep 27;7:e38636. doi: 10.7554/eLife.38636. Elife. 2018. PMID: 30260317 Free PMC article.
A small molecule inhibitor of HER3: a proof-of-concept study.
Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. Colomba A, et al. Among authors: george r. Biochem J. 2020 Sep 18;477(17):3329-3347. doi: 10.1042/BCJ20200496. Biochem J. 2020. PMID: 32815546 Free PMC article.
VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression.
Morini MF, Giampietro C, Corada M, Pisati F, Lavarone E, Cunha SI, Conze LL, O'Reilly N, Joshi D, Kjaer S, George R, Nye E, Ma A, Jin J, Mitter R, Lupia M, Cavallaro U, Pasini D, Calado DP, Dejana E, Taddei A. Morini MF, et al. Among authors: george r. Circ Res. 2018 Jan 19;122(2):231-245. doi: 10.1161/CIRCRESAHA.117.312392. Epub 2017 Dec 12. Circ Res. 2018. PMID: 29233846 Free PMC article.
2,707 results