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Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.
Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, Ramirez MA, Liang T, Caballero F, Wildschut MHE, Neel DV, Freeman DB, Pop MS, McConkey M, Muller S, Curtin BH, Tseng H, Frombach KR, Butty VL, Levine SS, Feau C, Elmiligy S, Hong JA, Lewis TA, Vetere A, Clemons PA, Malstrom SE, Ebert BL, Lin CY, Felsher DW, Koehler AN. Struntz NB, et al. Among authors: clemons pa. Cell Chem Biol. 2019 May 16;26(5):711-723.e14. doi: 10.1016/j.chembiol.2019.02.009. Epub 2019 Mar 14. Cell Chem Biol. 2019. PMID: 30880155 Free article.
A pipeline for ligand discovery using small-molecule microarrays.
Duffner JL, Clemons PA, Koehler AN. Duffner JL, et al. Among authors: clemons pa. Curr Opin Chem Biol. 2007 Feb;11(1):74-82. doi: 10.1016/j.cbpa.2006.11.031. Epub 2006 Dec 13. Curr Opin Chem Biol. 2007. PMID: 17169601 Review.
Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.
Chou DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, Wagner BK. Chou DH, et al. Among authors: clemons pa. ACS Chem Biol. 2010 Aug 20;5(8):729-34. doi: 10.1021/cb100129d. ACS Chem Biol. 2010. PMID: 20550176 Free PMC article.
A human islet cell culture system for high-throughput screening.
Walpita D, Hasaka T, Spoonamore J, Vetere A, Takane KK, Fomina-Yadlin D, Fiaschi-Taesch N, Shamji A, Clemons PA, Stewart AF, Schreiber SL, Wagner BK. Walpita D, et al. Among authors: clemons pa. J Biomol Screen. 2012 Apr;17(4):509-18. doi: 10.1177/1087057111430253. Epub 2011 Dec 7. J Biomol Screen. 2012. PMID: 22156222 Free PMC article.
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.
Kubicek S, Gilbert JC, Fomina-Yadlin D, Gitlin AD, Yuan Y, Wagner FF, Holson EB, Luo T, Lewis TA, Taylor B, Gupta S, Shamji AF, Wagner BK, Clemons PA, Schreiber SL. Kubicek S, et al. Among authors: clemons pa. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5364-9. doi: 10.1073/pnas.1201079109. Epub 2012 Mar 20. Proc Natl Acad Sci U S A. 2012. PMID: 22434908 Free PMC article.
123 results