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Page 1
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman S, Beilschmidt M, To M, Lin K, Lui F, Jmeian Y, Ng M, Fernandez M, Fu Y, Mascall K, Duque A, Wang X, Pan G, Angers S, Moffat J, Sidhu SS, Magram J, Sinclair AM, Fransson J, Julien JP. Raman S, et al. Among authors: magram j. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6812-6817. doi: 10.1073/pnas.1817246116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894493 Free PMC article.
Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption.
Johnson K, Levine K, Sergi J, Chamoun J, Roach R, Vekich J, Favis M, Horn M, Cao X, Miller B, Snyder W, Aivazian D, Reagan W, Berryman E, Colangelo J, Markiewicz V, Bagi CM, Brown TP, Coyle A, Mohammadi M, Magram J. Johnson K, et al. Among authors: magram j. J Bone Miner Res. 2017 Oct;32(10):2062-2073. doi: 10.1002/jbmr.3197. Epub 2017 Aug 25. J Bone Miner Res. 2017. PMID: 28600887 Free PMC article.
Meetings of the minds: maximizing drug discovery.
Magram J. Magram J. Dis Model Mech. 2008 Nov-Dec;1(4-5):192-4. doi: 10.1242/dmm.000893. Dis Model Mech. 2008. PMID: 19093018 Free PMC article. No abstract available.
Characterization of glucokinase regulatory protein-deficient mice.
Grimsby J, Coffey JW, Dvorozniak MT, Magram J, Li G, Matschinsky FM, Shiota C, Kaur S, Magnuson MA, Grippo JF. Grimsby J, et al. Among authors: magram j. J Biol Chem. 2000 Mar 17;275(11):7826-31. doi: 10.1074/jbc.275.11.7826. J Biol Chem. 2000. PMID: 10713097 Free article.
Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice.
Rakhit A, Yeon MM, Ferrante J, Fettner S, Nadeau R, Motzer R, Bukowski R, Carvajal DM, Wilkinson VL, Presky DH, Magram J, Gately MK. Rakhit A, et al. Among authors: magram j. Clin Pharmacol Ther. 1999 Jun;65(6):615-29. doi: 10.1016/S0009-9236(99)90083-8. Clin Pharmacol Ther. 1999. PMID: 10391667 Clinical Trial.
45 results