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The transcription Factor AHR prevents the differentiation of a stage 3 innate lymphoid cell subset to natural killer cells.
Hughes T, Briercheck EL, Freud AG, Trotta R, McClory S, Scoville SD, Keller K, Deng Y, Cole J, Harrison N, Mao C, Zhang J, Benson DM, Yu J, Caligiuri MA. Hughes T, et al. Among authors: scoville sd. Cell Rep. 2014 Jul 10;8(1):150-62. doi: 10.1016/j.celrep.2014.05.042. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953655 Free PMC article.
PTEN is a negative regulator of NK cell cytolytic function.
Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, Pilarski R, Carson WE 3rd, Leone G, Pandolfi PP, Yu J, Orange JS, Caligiuri MA. Briercheck EL, et al. Among authors: scoville sd. J Immunol. 2015 Feb 15;194(4):1832-40. doi: 10.4049/jimmunol.1401224. Epub 2015 Jan 16. J Immunol. 2015. PMID: 25595786 Free PMC article.
Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12.
Campbell AR, Regan K, Bhave N, Pattanayak A, Parihar R, Stiff AR, Trikha P, Scoville SD, Liyanarachchi S, Kondadasula SV, Lele O, Davuluri R, Payne PR, Carson WE 3rd. Campbell AR, et al. Among authors: scoville sd. BMC Med Genomics. 2015 Oct 15;8:66. doi: 10.1186/s12920-015-0142-9. BMC Med Genomics. 2015. PMID: 26470881 Free PMC article.
NKp80 Defines a Critical Step during Human Natural Killer Cell Development.
Freud AG, Keller KA, Scoville SD, Mundy-Bosse BL, Cheng S, Youssef Y, Hughes T, Zhang X, Mo X, Porcu P, Baiocchi RA, Yu J, Carson WE 3rd, Caligiuri MA. Freud AG, et al. Among authors: scoville sd. Cell Rep. 2016 Jul 12;16(2):379-391. doi: 10.1016/j.celrep.2016.05.095. Epub 2016 Jun 30. Cell Rep. 2016. PMID: 27373165 Free PMC article.
Human AML activates the aryl hydrocarbon receptor pathway to impair NK cell development and function.
Scoville SD, Nalin AP, Chen L, Chen L, Zhang MH, McConnell K, Beceiro Casas S, Ernst G, Traboulsi AA, Hashi N, Williams M, Zhang X, Hughes T, Mishra A, Benson DM, Saultz JN, Yu J, Freud AG, Caligiuri MA, Mundy-Bosse BL. Scoville SD, et al. Blood. 2018 Oct 25;132(17):1792-1804. doi: 10.1182/blood-2018-03-838474. Epub 2018 Aug 29. Blood. 2018. PMID: 30158248 Free PMC article.
58 results