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Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant.
Al-Mashhadi RH, Sørensen CB, Kragh PM, Christoffersen C, Mortensen MB, Tolbod LP, Thim T, Du Y, Li J, Liu Y, Moldt B, Schmidt M, Vajta G, Larsen T, Purup S, Bolund L, Nielsen LB, Callesen H, Falk E, Mikkelsen JG, Bentzon JF. Al-Mashhadi RH, et al. Among authors: tolbod lp. Sci Transl Med. 2013 Jan 2;5(166):166ra1. doi: 10.1126/scitranslmed.3004853. Sci Transl Med. 2013. PMID: 23283366
Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.
Poulsen CB, Al-Mashhadi AL, von Wachenfeldt K, Bentzon JF, Nielsen LB, Al-Mashhadi RH, Thygesen J, Tolbod L, Larsen JR, Frøkiær J, Tawakol A, Vucic E, Fredrickson J, Baruch A, Frendéus B, Robertson AK, Moestrup SK, Drouet L, Falk E. Poulsen CB, et al. Int J Cardiol. 2016 Jul 15;215:506-15. doi: 10.1016/j.ijcard.2016.03.222. Epub 2016 Apr 2. Int J Cardiol. 2016. PMID: 27135822
Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs.
Al-Mashhadi AL, Poulsen CB, von Wachenfeldt K, Robertson AK, Bentzon JF, Nielsen LB, Thygesen J, Tolbod LP, Larsen JR, Moestrup SK, Frendéus B, Mortensen B, Drouet L, Al-Mashhadi RH, Falk E. Al-Mashhadi AL, et al. Among authors: tolbod lp. J Diabetes Res. 2018 Feb 25;2018:6823193. doi: 10.1155/2018/6823193. eCollection 2018. J Diabetes Res. 2018. PMID: 29682581 Free PMC article.
74 results