Li Q - Search Results

1

Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors.

Ma J, Chen H, Yang J, Yu Z, Huang P, Yang H, Zheng B, Liu R, Li Q, Hu G, Chen Z. Ma J, et al. Among authors: li q. Bioorg Med Chem. 2019 May 1;27(9):1871-1881. doi: 10.1016/j.bmc.2019.03.037. Epub 2019 Mar 22. Bioorg Med Chem. 2019. PMID: 30926312

2

Novel 3-galloylamido-N'-substituted-2,6-piperidinedione-N-acetamide peptidomimetics as metalloproteinase inhibitors.

Li Q, Fang H, Xu W. Li Q, et al. Bioorg Med Chem Lett. 2007 May 15;17(10):2935-8. doi: 10.1016/j.bmcl.2006.12.095. Epub 2007 Jan 5. Bioorg Med Chem Lett. 2007. PMID: 17433673

3

Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Design, chemistry and activity evaluation. Part I.

Li Q, Fang H, Wang X, Hu L, Xu W. Li Q, et al. Eur J Med Chem. 2009 Dec;44(12):4819-25. doi: 10.1016/j.ejmech.2009.07.022. Epub 2009 Jul 30. Eur J Med Chem. 2009. PMID: 19683842

4

Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors.

Li Q, Al-Ayoubi A, Guo T, Zheng H, Sarkar A, Nguyen T, Eblen ST, Grant S, Kellogg GE, Zhang S. Li Q, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6042-6. doi: 10.1016/j.bmcl.2009.09.057. Epub 2009 Sep 18. Bioorg Med Chem Lett. 2009. PMID: 19796943 Free PMC article.

5

Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Structure-based design, chemistry and activity evaluation. II.

Li Q, Fang H, Wang X, Xu W. Li Q, et al. Eur J Med Chem. 2010 Apr;45(4):1618-26. doi: 10.1016/j.ejmech.2009.12.071. Epub 2010 Jan 14. Eur J Med Chem. 2010. PMID: 20129718

6

Discovery of 3-(2-aminoethyl)-5-(3-phenyl-propylidene)-thiazolidine-2,4-dione as a dual inhibitor of the Raf/MEK/ERK and the PI3K/Akt signaling pathways.

Li Q, Wu J, Zheng H, Liu K, Guo TL, Liu Y, Eblen ST, Grant S, Zhang S. Li Q, et al. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4526-30. doi: 10.1016/j.bmcl.2010.06.030. Epub 2010 Jun 8. Bioorg Med Chem Lett. 2010. PMID: 20580230

7

Novel aminopeptidase N (APN/CD13) inhibitors derived from 3-phenylalanyl-N'-substituted-2,6-piperidinedione.

Zhang X, Fang H, Zhu H, Wang X, Zhang L, Li M, Li Q, Yuan Y, Xu W. Zhang X, et al. Among authors: li m, li q. Bioorg Med Chem. 2010 Aug 15;18(16):5981-7. doi: 10.1016/j.bmc.2010.06.078. Epub 2010 Jun 26. Bioorg Med Chem. 2010. PMID: 20637634

8

3,5-Disubstituted-thiazolidine-2,4-dione analogs as anticancer agents: design, synthesis and biological characterization.

Liu K, Rao W, Parikh H, Li Q, Guo TL, Grant S, Kellogg GE, Zhang S. Liu K, et al. Among authors: li q. Eur J Med Chem. 2012 Jan;47(1):125-37. doi: 10.1016/j.ejmech.2011.10.031. Epub 2011 Oct 21. Eur J Med Chem. 2012. PMID: 22074985

9

Novel potent 2,5-pyrrolidinedione peptidomimetics as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.

Li Q, Fang H, Wang X, Hu G, Wang Q, Xu W. Li Q, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):850-3. doi: 10.1016/j.bmcl.2011.12.048. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22206607

10

Synthesis, pharmacokinetics, and pharmacodynamics studies of valsartan peptide derivatives.

Wu C, Hu Y, Li Q, He L, Chen J, Cheng Z, Li Y, Hu G. Wu C, et al. Among authors: li y, li q. Arch Pharm (Weinheim). 2012 May;345(5):393-400. doi: 10.1002/ardp.201100377. Epub 2012 Jan 20. Arch Pharm (Weinheim). 2012. PMID: 22266917

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