Charles RP - Search Results

1

Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy.

Schürch CM, Roelli MA, Forster S, Wasmer MH, Brühl F, Maire RS, Di Pancrazio S, Ruepp MD, Giger R, Perren A, Schmitt AM, Krebs P, Charles RP, Dettmer MS. Schürch CM, et al. Among authors: charles rp. Thyroid. 2019 Jul;29(7):979-992. doi: 10.1089/thy.2018.0555. Epub 2019 May 10. Thyroid. 2019. PMID: 30938231 Free PMC article.

2

BRAF^V600E Overrides NOTCH Signaling in Thyroid Cancer.

Traversi F, Stooss A, Dettmer MS, Charles RP. Traversi F, et al. Among authors: charles rp. Thyroid. 2021 May;31(5):787-799. doi: 10.1089/thy.2019.0595. Epub 2020 Nov 12. Thyroid. 2021. PMID: 33012268

3

MEK Inhibition Induces Therapeutic Iodine Uptake in a Murine Model of Anaplastic Thyroid Cancer.

ElMokh O, Taelman V, Radojewski P, Roelli MA, Stoss A, Dumont RA, Dettmer MS, Phillips WA, Walter MA, Charles RP. ElMokh O, et al. Among authors: charles rp. J Nucl Med. 2019 Jul;60(7):917-923. doi: 10.2967/jnumed.118.216721. Epub 2018 Nov 21. J Nucl Med. 2019. PMID: 30464041 Free article.

4

Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.

ElMokh O, Ruffieux-Daidié D, Roelli MA, Stooss A, Phillips WA, Gertsch J, Dettmer MS, Charles RP. ElMokh O, et al. Among authors: charles rp. Oncotarget. 2017 Apr 11;8(15):24604-24620. doi: 10.18632/oncotarget.15599. Oncotarget. 2017. PMID: 28445948 Free PMC article.

5

The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model.

Häfliger P, Graff J, Rubin M, Stooss A, Dettmer MS, Altmann KH, Gertsch J, Charles RP. Häfliger P, et al. Among authors: charles rp. J Exp Clin Cancer Res. 2018 Sep 21;37(1):234. doi: 10.1186/s13046-018-0907-z. J Exp Clin Cancer Res. 2018. PMID: 30241549 Free PMC article.

6

PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models.

Nisa L, Häfliger P, Poliaková M, Giger R, Francica P, Aebersold DM, Charles RP, Zimmer Y, Medová M. Nisa L, et al. Among authors: charles rp. Mol Cancer. 2017 May 22;16(1):93. doi: 10.1186/s12943-017-0660-5. Mol Cancer. 2017. PMID: 28532501 Free PMC article.

7

PIK3CA^H1047R-induced paradoxical ERK activation results in resistance to BRAF^V600E specific inhibitors in BRAF^V600E PIK3CA^H1047R double mutant thyroid tumors.

Roelli MA, Ruffieux-Daidié D, Stooss A, ElMokh O, Phillips WA, Dettmer MS, Charles RP. Roelli MA, et al. Among authors: charles rp. Oncotarget. 2017 Oct 11;8(61):103207-103222. doi: 10.18632/oncotarget.21732. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262556 Free PMC article.

8

Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2.

Poirier M, Awale M, Roelli MA, Giuffredi GT, Ruddigkeit L, Evensen L, Stooss A, Calarco S, Lorens JB, Charles RP, Reymond JL. Poirier M, et al. Among authors: charles rp. ChemMedChem. 2019 Jan 22;14(2):224-236. doi: 10.1002/cmdc.201800554. Epub 2018 Dec 6. ChemMedChem. 2019. PMID: 30520265

9

Overview of Genetically Engineered Mouse Models of Papillary and Anaplastic Thyroid Cancers: Enabling Translational Biology for Patient Care Improvement.

Charles RP. Charles RP. Curr Protoc Pharmacol. 2015 Jun 1;69:14.33.1-14.33.14. doi: 10.1002/0471141755.ph1433s69. Curr Protoc Pharmacol. 2015. PMID: 26344211 Review.

10

Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis.

Charles RP, Silva J, Iezza G, Phillips WA, McMahon M. Charles RP, et al. Mol Cancer Res. 2014 Jul;12(7):979-86. doi: 10.1158/1541-7786.MCR-14-0158-T. Epub 2014 Apr 25. Mol Cancer Res. 2014. PMID: 24770869 Free PMC article.

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