Meanwell NA - Search Results

1

Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir.

A M Subbaiah M, Mandlekar S, Desikan S, Ramar T, Subramani L, Annadurai M, Desai SD, Sinha S, Jenkins SM, Krystal MR, Subramanian M, Sridhar S, Padmanabhan S, Bhutani P, Arla R, Singh S, Sinha J, Thakur M, Kadow JF, Meanwell NA. A M Subbaiah M, et al. Among authors: meanwell na. J Med Chem. 2019 Apr 11;62(7):3553-3574. doi: 10.1021/acs.jmedchem.9b00002. Epub 2019 Apr 2. J Med Chem. 2019. PMID: 30938524

2

A strategy for the synthesis of aryl alpha-ketoamides based upon the acylation of anions derived from cyanomethylamines followed by oxidative cleavage.

Yang Z, Zhang Z, Meanwell NA, Kadow JF, Wang T. Yang Z, et al. Among authors: meanwell na. Org Lett. 2002 Apr 4;4(7):1103-5. doi: 10.1021/ol010297l. Org Lett. 2002. PMID: 11922793

3

A general method for the preparation of 4- and 6-azaindoles.

Zhang Z, Yang Z, Meanwell NA, Kadow JF, Wang T. Zhang Z, et al. Among authors: meanwell na. J Org Chem. 2002 Apr 5;67(7):2345-7. doi: 10.1021/jo0111614. J Org Chem. 2002. PMID: 11925251

4

An effective procedure for the acylation of azaindoles at C-3.

Zhang Z, Yang Z, Wong H, Zhu J, Meanwell NA, Kadow JF, Wang T. Zhang Z, et al. Among authors: meanwell na. J Org Chem. 2002 Aug 23;67(17):6226-7. doi: 10.1021/jo020135i. J Org Chem. 2002. PMID: 12182666

5

Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.

Yu KL, Torri AF, Luo G, Cianci C, Grant-Young K, Danetz S, Tiley L, Krystal M, Meanwell NA. Yu KL, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3379-82. doi: 10.1016/s0960-894x(02)00761-8. Bioorg Med Chem Lett. 2002. PMID: 12419365

6

Fundamental structure-activity relationships associated with a new structural class of respiratory syncytial virus inhibitor.

Yu KL, Zhang Y, Civiello RL, Kadow KF, Cianci C, Krystal M, Meanwell NA. Yu KL, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2141-4. doi: 10.1016/s0960-894x(03)00383-4. Bioorg Med Chem Lett. 2003. PMID: 12798322

7

Inhibitors of the entry of HIV into host cells.

Meanwell NA, Kadow JF. Meanwell NA, et al. Curr Opin Drug Discov Devel. 2003 Jul;6(4):451-61. Curr Opin Drug Discov Devel. 2003. PMID: 12951808 Review.

8

Selective monoacylation of symmetrical diamines via prior complexation with boron.

Zhang Z, Yin Z, Meanwell NA, Kadow JF, Wang T. Zhang Z, et al. Among authors: meanwell na. Org Lett. 2003 Sep 18;5(19):3399-402. doi: 10.1021/ol0300773. Org Lett. 2003. PMID: 12967284

9

Dialkylaminoacetonitrile derivatives as amide synthons. A one-pot preparation of heteroaryl amides via a strategy of sequential SNAr substitution and oxidation.

Zhang Z, Yin Z, Kadow JF, Meanwell NA, Wang T. Zhang Z, et al. Among authors: meanwell na. J Org Chem. 2004 Feb 20;69(4):1360-3. doi: 10.1021/jo030233j. J Org Chem. 2004. PMID: 14961692

10

Acetonitrile derivatives as carbonyl synthons. One-pot preparation of diheteroaryl ketones via a strategy of sequential SNAr substitution and oxidation.

Yin Z, Zhang Z, Kadow JF, Meanwell NA, Wang T. Yin Z, et al. Among authors: meanwell na. J Org Chem. 2004 Feb 20;69(4):1364-7. doi: 10.1021/jo030234b. J Org Chem. 2004. PMID: 14961693

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