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TRPV1 promotes opioid analgesia during inflammation.
Basso L, Aboushousha R, Fan CY, Iftinca M, Melo H, Flynn R, Agosti F, Hollenberg MD, Thompson R, Bourinet E, Trang T, Altier C. Basso L, et al. Among authors: thompson r. Sci Signal. 2019 Apr 2;12(575):eaav0711. doi: 10.1126/scisignal.aav0711. Sci Signal. 2019. PMID: 30940767
Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry.
Kwok CHT, Harding EK, Burma NE, Markovic T, Massaly N, van den Hoogen NJ, Stokes-Heck S, Gambeta E, Komarek K, Yoon HJ, Navis KE, McAllister BB, Canet-Pons J, Fan C, Dalgarno R, Gorobets E, Papatzimas JW, Zhang Z, Kohro Y, Anderson CL, Thompson RJ, Derksen DJ, Morón JA, Zamponi GW, Trang T. Kwok CHT, et al. Among authors: thompson rj. Nat Commun. 2024 Jul 24;15(1):6264. doi: 10.1038/s41467-024-50657-7. Nat Commun. 2024. PMID: 39048565 Free PMC article.
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.
Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE. Billaud M, et al. Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824. Sci Signal. 2015. PMID: 25690012 Free PMC article.
8,446 results