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329 results

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Page 1
FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.
Hyrenius-Wittsten A, Pilheden M, Falqués-Costa A, Eriksson M, Sturesson H, Schneider P, Wander P, Garcia-Ruiz C, Liu J, Ågerstam H, Hultquist A, Lilljebjörn H, Stam RW, Järås M, Hagström-Andersson AK. Hyrenius-Wittsten A, et al. Leukemia. 2019 Sep;33(9):2310-2314. doi: 10.1038/s41375-019-0465-1. Epub 2019 Apr 5. Leukemia. 2019. PMID: 30953031 Free PMC article. No abstract available.
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
Hyrenius-Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh MP, Song G, Kazi JU, Liu J, Ramakrishan R, Garcia-Ruiz C, Nance S, Gupta P, Zhang J, Rönnstrand L, Hultquist A, Downing JR, Lindkvist-Petersson K, Paulsson K, Järås M, Gruber TA, Ma J, Hagström-Andersson AK. Hyrenius-Wittsten A, et al. Nat Commun. 2018 May 2;9(1):1770. doi: 10.1038/s41467-018-04180-1. Nat Commun. 2018. PMID: 29720585 Free PMC article.
Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice.
Garcia-Ruiz C, Martínez-Valiente C, Cordón L, Liquori A, Fernández-González R, Pericuesta E, Sandoval J, Cervera J, Gutiérrez-Adán A, Sanjuan-Pla A. Garcia-Ruiz C, et al. Leukemia. 2022 Oct;36(10):2509-2518. doi: 10.1038/s41375-022-01674-2. Epub 2022 Aug 27. Leukemia. 2022. PMID: 36030305 Free PMC article.
A Single-Run Next-Generation Sequencing (NGS) Assay for the Simultaneous Detection of Both Gene Mutations and Large Chromosomal Abnormalities in Patients with Myelodysplastic Syndromes (MDS) and Related Myeloid Neoplasms.
Liquori A, Lesende I, Palomo L, Avetisyan G, Ibáñez M, González-Romero E, Boluda-Navarro M, Morote-Faubel M, Garcia-Ruiz C, Martinez-Valiente C, Santiago-Balsera M, Gomez-Seguí I, Sanjuan-Pla A, Sanz MA, Sanz G, Solé F, Such E, Cervera J. Liquori A, et al. Cancers (Basel). 2021 Apr 18;13(8):1947. doi: 10.3390/cancers13081947. Cancers (Basel). 2021. PMID: 33919541 Free PMC article.
CRISPR to fix bad blood: a new tool in basic and clinical hematology.
González-Romero E, Martínez-Valiente C, García-Ruiz C, Vázquez-Manrique RP, Cervera J, Sanjuan-Pla A. González-Romero E, et al. Haematologica. 2019 May;104(5):881-893. doi: 10.3324/haematol.2018.211359. Epub 2019 Mar 28. Haematologica. 2019. PMID: 30923099 Free PMC article. Review.
Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.
Mohlin S, Hansson K, Radke K, Martinez S, Blanco-Aparicio C, Garcia-Ruiz C, Welinder C, Esfandyari J, O'Neill M, Pastor J, von Stedingk K, Bexell D. Mohlin S, et al. EMBO Mol Med. 2020 Jan 9;12(1):e11749. doi: 10.15252/emmm.201911749. EMBO Mol Med. 2020. PMID: 31916402 Free PMC article. No abstract available.
Stard1 promotes cholestatic liver injury and disease progression by sensitizing to bile acid hepatotoxicity.
Conde de la Rosa L, Fábrega L, Torres S, Nuñez S, Ribas V, Segalés P, Espinosa-Escudero R, Solsona E, Monte MJ, Diaz-Gonzalez A, Marin JJG, García-Ruiz C, Fernandez-Checa JC. Conde de la Rosa L, et al. Among authors: garcia ruiz c. Hepatology. 2024 Dec 9. doi: 10.1097/HEP.0000000000001184. Online ahead of print. Hepatology. 2024. PMID: 39652774
Palmitoylcarnitine impairs immunity in decompensated cirrhosis.
Zhang IW, Sánchez-Rodríguez MB, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Aguilar F, Rothe M, Segalés P, García-Ruiz C, Fernández-Checa JC, Trebicka J, Arroyo V, Clària J. Zhang IW, et al. Among authors: garcia ruiz c. JHEP Rep. 2024 Aug 22;6(11):101187. doi: 10.1016/j.jhepr.2024.101187. eCollection 2024 Nov. JHEP Rep. 2024. PMID: 39524205 Free PMC article.
329 results