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Page 1
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids.
Bolhaqueiro ACF, Ponsioen B, Bakker B, Klaasen SJ, Kucukkose E, van Jaarsveld RH, Vivié J, Verlaan-Klink I, Hami N, Spierings DCJ, Sasaki N, Dutta D, Boj SF, Vries RGJ, Lansdorp PM, van de Wetering M, van Oudenaarden A, Clevers H, Kranenburg O, Foijer F, Snippert HJG, Kops GJPL. Bolhaqueiro ACF, et al. Among authors: kranenburg o. Nat Genet. 2019 May;51(5):824-834. doi: 10.1038/s41588-019-0399-6. Epub 2019 Apr 29. Nat Genet. 2019. PMID: 31036964
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.
Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Among authors: kranenburg o. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.
Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.
Vellinga TT, den Uil S, Rinkes IH, Marvin D, Ponsioen B, Alvarez-Varela A, Fatrai S, Scheele C, Zwijnenburg DA, Snippert H, Vermeulen L, Medema JP, Stockmann HB, Koster J, Fijneman RJ, de Rooij J, Kranenburg O. Vellinga TT, et al. Among authors: kranenburg o. Oncogene. 2016 Oct 6;35(40):5263-5271. doi: 10.1038/onc.2016.60. Epub 2016 Mar 21. Oncogene. 2016. PMID: 26996663
Mouse and human urothelial cancer organoids: A tool for bladder cancer research.
Mullenders J, de Jongh E, Brousali A, Roosen M, Blom JPA, Begthel H, Korving J, Jonges T, Kranenburg O, Meijer R, Clevers HC. Mullenders J, et al. Among authors: kranenburg o. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4567-4574. doi: 10.1073/pnas.1803595116. Epub 2019 Feb 20. Proc Natl Acad Sci U S A. 2019. PMID: 30787188 Free PMC article.
Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy.
Driehuis E, Kolders S, Spelier S, Lõhmussaar K, Willems SM, Devriese LA, de Bree R, de Ruiter EJ, Korving J, Begthel H, van Es JH, Geurts V, He GW, van Jaarsveld RH, Oka R, Muraro MJ, Vivié J, Zandvliet MMJM, Hendrickx APA, Iakobachvili N, Sridevi P, Kranenburg O, van Boxtel R, Kops GJPL, Tuveson DA, Peters PJ, van Oudenaarden A, Clevers H. Driehuis E, et al. Among authors: kranenburg o. Cancer Discov. 2019 Jul;9(7):852-871. doi: 10.1158/2159-8290.CD-18-1522. Epub 2019 May 3. Cancer Discov. 2019. PMID: 31053628
Organoids from colorectal peritoneal metastases as a platform for improving hyperthermic intraperitoneal chemotherapy.
Ubink I, Bolhaqueiro ACF, Elias SG, Raats DAE, Constantinides A, Peters NA, Wassenaar ECE, de Hingh IHJT, Rovers KP, van Grevenstein WMU, Laclé MM, Kops GJPL, Borel Rinkes IHM, Kranenburg O. Ubink I, et al. Among authors: kranenburg o. Br J Surg. 2019 Sep;106(10):1404-1414. doi: 10.1002/bjs.11206. Epub 2019 Jun 14. Br J Surg. 2019. PMID: 31197820 Free PMC article.
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
Driehuis E, van Hoeck A, Moore K, Kolders S, Francies HE, Gulersonmez MC, Stigter ECA, Burgering B, Geurts V, Gracanin A, Bounova G, Morsink FH, Vries R, Boj S, van Es J, Offerhaus GJA, Kranenburg O, Garnett MJ, Wessels L, Cuppen E, Brosens LAA, Clevers H. Driehuis E, et al. Among authors: kranenburg o. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26580-26590. doi: 10.1073/pnas.1911273116. Epub 2019 Dec 9. Proc Natl Acad Sci U S A. 2019. PMID: 31818951 Free PMC article.
A review of the sensitivity of metastatic colorectal cancer patients with deficient mismatch repair to standard-of-care chemotherapy and monoclonal antibodies, with recommendations for future research.
Wensink E, Bond M, Kucukkose E, May A, Vink G, Koopman M, Kranenburg O, Roodhart J. Wensink E, et al. Among authors: kranenburg o. Cancer Treat Rev. 2021 Apr;95:102174. doi: 10.1016/j.ctrv.2021.102174. Epub 2021 Mar 1. Cancer Treat Rev. 2021. PMID: 33721596 Free article. Review.
190 results