Fidock DA - Search Results

1

Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness.

Dhingra SK, Gabryszewski SJ, Small-Saunders JL, Yeo T, Henrich PP, Mok S, Fidock DA. Dhingra SK, et al. Among authors: fidock da. mBio. 2019 Apr 30;10(2):e02731-18. doi: 10.1128/mBio.02731-18. mBio. 2019. PMID: 31040246 Free PMC article.

2

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, Su XZ, Wootton JC, Roepe PD, Wellems TE. Fidock DA, et al. Mol Cell. 2000 Oct;6(4):861-71. doi: 10.1016/s1097-2765(05)00077-8. Mol Cell. 2000. PMID: 11090624 Free PMC article.

3

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Cooper RA, et al. Among authors: fidock da. Mol Pharmacol. 2002 Jan;61(1):35-42. doi: 10.1124/mol.61.1.35. Mol Pharmacol. 2002. PMID: 11752204

4

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.

Sidhu AB, Verdier-Pinard D, Fidock DA. Sidhu AB, et al. Among authors: fidock da. Science. 2002 Oct 4;298(5591):210-3. doi: 10.1126/science.1074045. Science. 2002. PMID: 12364805 Free PMC article.

5

Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter.

Waller KL, Muhle RA, Ursos LM, Horrocks P, Verdier-Pinard D, Sidhu AB, Fujioka H, Roepe PD, Fidock DA. Waller KL, et al. Among authors: fidock da. J Biol Chem. 2003 Aug 29;278(35):33593-601. doi: 10.1074/jbc.M302215200. Epub 2003 Jun 17. J Biol Chem. 2003. PMID: 12813054 Free article.

6

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.

Lakshmanan V, Bray PG, Verdier-Pinard D, Johnson DJ, Horrocks P, Muhle RA, Alakpa GE, Hughes RH, Ward SA, Krogstad DJ, Sidhu AB, Fidock DA. Lakshmanan V, et al. Among authors: fidock da. EMBO J. 2005 Jul 6;24(13):2294-305. doi: 10.1038/sj.emboj.7600681. Epub 2005 Jun 9. EMBO J. 2005. PMID: 15944738 Free PMC article.

7

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.

Sidhu AB, Uhlemann AC, Valderramos SG, Valderramos JC, Krishna S, Fidock DA. Sidhu AB, et al. Among authors: fidock da. J Infect Dis. 2006 Aug 15;194(4):528-35. doi: 10.1086/507115. Epub 2006 Jul 11. J Infect Dis. 2006. PMID: 16845638 Free PMC article.

8

Transporters involved in resistance to antimalarial drugs.

Valderramos SG, Fidock DA. Valderramos SG, et al. Among authors: fidock da. Trends Pharmacol Sci. 2006 Nov;27(11):594-601. doi: 10.1016/j.tips.2006.09.005. Epub 2006 Sep 25. Trends Pharmacol Sci. 2006. PMID: 16996622 Free PMC article. Review.

9

Advances in understanding the genetic basis of antimalarial drug resistance.

Ekland EH, Fidock DA. Ekland EH, et al. Among authors: fidock da. Curr Opin Microbiol. 2007 Aug;10(4):363-70. doi: 10.1016/j.mib.2007.07.007. Epub 2007 Aug 20. Curr Opin Microbiol. 2007. PMID: 17709280 Free PMC article. Review.

10

Recent highlights in antimalarial drug resistance and chemotherapy research.

Fidock DA, Eastman RT, Ward SA, Meshnick SR. Fidock DA, et al. Trends Parasitol. 2008 Dec;24(12):537-44. doi: 10.1016/j.pt.2008.09.005. Epub 2008 Oct 18. Trends Parasitol. 2008. PMID: 18938106 Free PMC article. Review.

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