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Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter.
Petersen I, Gabryszewski SJ, Johnston GL, Dhingra SK, Ecker A, Lewis RE, de Almeida MJ, Straimer J, Henrich PP, Palatulan E, Johnson DJ, Coburn-Flynn O, Sanchez C, Lehane AM, Lanzer M, Fidock DA. Petersen I, et al. Among authors: gabryszewski sj. Mol Microbiol. 2015 Jul;97(2):381-95. doi: 10.1111/mmi.13035. Epub 2015 May 20. Mol Microbiol. 2015. PMID: 25898991 Free PMC article.
Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.
Pelleau S, Moss EL, Dhingra SK, Volney B, Casteras J, Gabryszewski SJ, Volkman SK, Wirth DF, Legrand E, Fidock DA, Neafsey DE, Musset L. Pelleau S, et al. Among authors: gabryszewski sj. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11672-7. doi: 10.1073/pnas.1507142112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261345 Free PMC article.
Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology.
Gabryszewski SJ, Dhingra SK, Combrinck JM, Lewis IA, Callaghan PS, Hassett MR, Siriwardana A, Henrich PP, Lee AH, Gnädig NF, Musset L, Llinás M, Egan TJ, Roepe PD, Fidock DA. Gabryszewski SJ, et al. PLoS Pathog. 2016 Nov 10;12(11):e1005976. doi: 10.1371/journal.ppat.1005976. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27832198 Free PMC article.
Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation.
Tomlinson KL, Lung TWF, Dach F, Annavajhala MK, Gabryszewski SJ, Groves RA, Drikic M, Francoeur NJ, Sridhar SH, Smith ML, Khanal S, Britto CJ, Sebra R, Lewis I, Uhlemann AC, Kahl BC, Prince AS, Riquelme SA. Tomlinson KL, et al. Among authors: gabryszewski sj. Nat Commun. 2021 Mar 3;12(1):1399. doi: 10.1038/s41467-021-21718-y. Nat Commun. 2021. PMID: 33658521 Free PMC article.
Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia.
Gabryszewski SJ, Wong Fok Lung T, Annavajhala MK, Tomlinson KL, Riquelme SA, Khan IN, Noguera LP, Wickersham M, Zhao A, Mulenos AM, Peaper D, Koff JL, Uhlemann AC, Prince A. Gabryszewski SJ, et al. Am J Respir Cell Mol Biol. 2019 Aug;61(2):185-197. doi: 10.1165/rcmb.2018-0389OC. Am J Respir Cell Mol Biol. 2019. PMID: 30742488 Free PMC article.
Self-Limited COVID-19 in a Patient with Artemis Hypomorphic SCID.
Gabryszewski SJ, England RN, Sun D, Gentile TL, Hochgertel W, Jyonouchi S, Silverman M, Zaoutis T, Sullivan KE, Henrickson SE. Gabryszewski SJ, et al. J Clin Immunol. 2021 Nov;41(8):1745-1747. doi: 10.1007/s10875-021-01093-5. Epub 2021 Aug 21. J Clin Immunol. 2021. PMID: 34420125 Free PMC article. No abstract available.
21 results