Reilly SW - Search Results

1

Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.

Makvandi M, Lee H, Puentes LN, Reilly SW, Rathi KS, Weng CC, Chan HS, Hou C, Raman P, Martinez D, Xu K, Carlin SD, Greenberg RA, Pawel BR, Mach RH, Maris JM, Pryma DA. Makvandi M, et al. Among authors: reilly sw. Mol Cancer Ther. 2019 Jul;18(7):1195-1204. doi: 10.1158/1535-7163.MCT-18-0837. Epub 2019 May 9. Mol Cancer Ther. 2019. PMID: 31072830 Free PMC article.

2

Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity.

Reilly SW, Puentes LN, Wilson K, Hsieh CJ, Weng CC, Makvandi M, Mach RH. Reilly SW, et al. J Med Chem. 2018 Jun 28;61(12):5367-5379. doi: 10.1021/acs.jmedchem.8b00576. Epub 2018 Jun 14. J Med Chem. 2018. PMID: 29856625 Free PMC article.

3

Synthesis and evaluation of an AZD2461 [¹⁸F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant.

Reilly SW, Puentes LN, Schmitz A, Hsieh CJ, Weng CC, Hou C, Li S, Kuo YM, Padakanti P, Lee H, Riad AA, Makvandi M, Mach RH. Reilly SW, et al. Bioorg Chem. 2019 Mar;83:242-249. doi: 10.1016/j.bioorg.2018.10.015. Epub 2018 Oct 17. Bioorg Chem. 2019. PMID: 30390553 Free PMC article.

4

Evaluation of a Low-Toxicity PARP Inhibitor as a Neuroprotective Agent for Parkinson's Disease.

Puentes LN, Lengyel-Zhand Z, Reilly SW, Mach RH. Puentes LN, et al. Among authors: reilly sw. Mol Neurobiol. 2021 Aug;58(8):3641-3652. doi: 10.1007/s12035-021-02371-4. Epub 2021 Mar 31. Mol Neurobiol. 2021. PMID: 33788167

5

Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase-1 Inhibitors with Decreased P-Glycoprotein Interactions.

Reilly SW, Puentes LN, Hsieh CJ, Makvandi M, Mach RH. Reilly SW, et al. ACS Omega. 2018 Aug 31;3(8):9997-10001. doi: 10.1021/acsomega.8b00896. Epub 2018 Aug 28. ACS Omega. 2018. PMID: 30198004 Free PMC article.

6

Pd-Catalyzed Synthesis of Piperazine Scaffolds Under Aerobic and Solvent-Free Conditions.

Reilly SW, Mach RH. Reilly SW, et al. Org Lett. 2016 Oct 21;18(20):5272-5275. doi: 10.1021/acs.orglett.6b02591. Epub 2016 Oct 13. Org Lett. 2016. PMID: 27736075 Free PMC article.

7

Rapid Cu-Catalyzed [²¹¹At]Astatination and [¹²⁵I]Iodination of Boronic Esters at Room Temperature.

Reilly SW, Makvandi M, Xu K, Mach RH. Reilly SW, et al. Org Lett. 2018 Apr 6;20(7):1752-1755. doi: 10.1021/acs.orglett.8b00232. Epub 2018 Mar 21. Org Lett. 2018. PMID: 29561158 Free PMC article.

8

Highly Selective Dopamine D₃ Receptor Antagonists with Arylated Diazaspiro Alkane Cores.

Reilly SW, Griffin S, Taylor M, Sahlholm K, Weng CC, Xu K, Jacome DA, Luedtke RR, Mach RH. Reilly SW, et al. J Med Chem. 2017 Dec 14;60(23):9905-9910. doi: 10.1021/acs.jmedchem.7b01248. Epub 2017 Nov 21. J Med Chem. 2017. PMID: 29125762 Free PMC article.

9

Pd-catalyzed arylation of linear and angular spirodiamine salts under aerobic conditions.

Reilly SW, Bryan NW, Mach RH. Reilly SW, et al. Tetrahedron Lett. 2017 Feb 1;58(5):466-469. doi: 10.1016/j.tetlet.2016.12.063. Epub 2016 Dec 23. Tetrahedron Lett. 2017. PMID: 31762498 Free PMC article.

10

Improved production of ⁷⁶Br, ⁷⁷Br and ^80mBr via CoSe cyclotron targets and vertical dry distillation.

Ellison PA, Olson AP, Barnhart TE, Hoffman SLV, Reilly SW, Makvandi M, Bartels JL, Murali D, DeJesus OT, Lapi SE, Bednarz B, Nickles RJ, Mach RH, Engle JW. Ellison PA, et al. Among authors: reilly sw. Nucl Med Biol. 2020 Jan-Feb;80-81:32-36. doi: 10.1016/j.nucmedbio.2019.09.001. Epub 2019 Sep 5. Nucl Med Biol. 2020. PMID: 31575457 Free PMC article.

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