Silva A - Search Results

1

Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs.

Clemens DL, Lee BY, Silva A, Dillon BJ, Masleša-Galić S, Nava S, Ding X, Ho CM, Horwitz MA. Clemens DL, et al. Among authors: silva a. PLoS One. 2019 May 10;14(5):e0215607. doi: 10.1371/journal.pone.0215607. eCollection 2019. PLoS One. 2019. PMID: 31075149 Free PMC article.

2

Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model.

Silva A, Lee BY, Clemens DL, Kee T, Ding X, Ho CM, Horwitz MA. Silva A, et al. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2172-9. doi: 10.1073/pnas.1600812113. Epub 2016 Mar 28. Proc Natl Acad Sci U S A. 2016. PMID: 27035987 Free PMC article.

3

Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time.

Lee BY, Clemens DL, Silva A, Dillon BJ, Masleša-Galić S, Nava S, Ding X, Ho CM, Horwitz MA. Lee BY, et al. Among authors: silva a. Nat Commun. 2017 Jan 24;8:14183. doi: 10.1038/ncomms14183. Nat Commun. 2017. PMID: 28117835 Free PMC article.

4

Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility.

Lee BY, Clemens DL, Silva A, Dillon BJ, Masleša-Galić S, Nava S, Ho CM, Horwitz MA. Lee BY, et al. Among authors: silva a. PLoS One. 2018 Nov 14;13(11):e0207469. doi: 10.1371/journal.pone.0207469. eCollection 2018. PLoS One. 2018. PMID: 30427938 Free PMC article.

5

Mechanism-independent optimization of combinatorial nanodiamond and unmodified drug delivery using a phenotypically driven platform technology.

Wang H, Lee DK, Chen KY, Chen JY, Zhang K, Silva A, Ho CM, Ho D. Wang H, et al. Among authors: silva a. ACS Nano. 2015 Mar 24;9(3):3332-44. doi: 10.1021/acsnano.5b00638. Epub 2015 Feb 23. ACS Nano. 2015. PMID: 25689511

6

When Medicine Meets Engineering-Paradigm Shifts in Diagnostics and Therapeutics.

Wang H, Silva A, Ho CM. Wang H, et al. Among authors: silva a. Diagnostics (Basel). 2013 Feb 27;3(1):126-54. doi: 10.3390/diagnostics3010126. Diagnostics (Basel). 2013. PMID: 26835672 Free PMC article. Review.

7

Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP).

Rashid MBMA, Toh TB, Hooi L, Silva A, Zhang Y, Tan PF, Teh AL, Karnani N, Jha S, Ho CM, Chng WJ, Ho D, Chow EK. Rashid MBMA, et al. Among authors: silva a. Sci Transl Med. 2018 Aug 8;10(453):eaan0941. doi: 10.1126/scitranslmed.aan0941. Sci Transl Med. 2018. PMID: 30089632

8

Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform.

Zarrinpar A, Lee DK, Silva A, Datta N, Kee T, Eriksen C, Weigle K, Agopian V, Kaldas F, Farmer D, Wang SE, Busuttil R, Ho CM, Ho D. Zarrinpar A, et al. Among authors: silva a. Sci Transl Med. 2016 Apr 6;8(333):333ra49. doi: 10.1126/scitranslmed.aac5954. Sci Transl Med. 2016. PMID: 27053773 Free article.

9

Identification and Optimization of Combinatorial Glucose Metabolism Inhibitors in Hepatocellular Carcinomas.

Mohd Abdul Rashid MB, Toh TB, Silva A, Nurrul Abdullah L, Ho CM, Ho D, Chow EK. Mohd Abdul Rashid MB, et al. Among authors: silva a. J Lab Autom. 2015 Aug;20(4):423-37. doi: 10.1177/2211068215579612. Epub 2015 Mar 30. J Lab Autom. 2015. PMID: 25824204

10

Clinical impact of healthcare-associated infections in Brazilian ICUs: a multicenter prospective cohort.

Tomazini BM, Besen BAMP, Santos RHN, Nassar AP Jr, Veiga TS, Campos VB, Tokunaga SM, Santos ES, Barbante LG, da Costa Maia R, Kojima FCS, Laranjeira LN, Taniguchi LU, Roepke RML, Franke CA, Sanches LC, Melro LMG, Maia IS, de Souza Dantas VC, Figueiredo RC, de Alencar Filho MS, Irineu VM, Lovato WJ, Zandonai CL, Machado FR, Arns B, Marsola G, Veiga VC, Pereira AJ, Cavalcanti AB; IMPACTO-MR investigators (2019 - 2023); BRICNet. Tomazini BM, et al. Crit Care. 2025 Jan 3;29(1):4. doi: 10.1186/s13054-024-05203-8. Crit Care. 2025. PMID: 39754200 Free PMC article.

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