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53 results

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Page 1
Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.
Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G. Tornatore L, et al. Among authors: d andrea d, capece d. Toxicol Rep. 2019 Apr 19;6:369-379. doi: 10.1016/j.toxrep.2019.04.006. eCollection 2019. Toxicol Rep. 2019. PMID: 31080744 Free PMC article.
Acyl-Carnitines Exert Positive Effects on Mitochondrial Activity under Oxidative Stress in Mouse Oocytes: A Potential Mechanism Underlying Carnitine Efficacy on PCOS.
Placidi M, Vergara T, Casoli G, Flati I, Capece D, Artini PG, Virmani A, Zanatta S, D'Alessandro AM, Tatone C, Di Emidio G. Placidi M, et al. Among authors: capece d. Biomedicines. 2023 Sep 6;11(9):2474. doi: 10.3390/biomedicines11092474. Biomedicines. 2023. PMID: 37760915 Free PMC article.
Targeting costimulatory molecules to improve antitumor immunity.
Capece D, Verzella D, Fischietti M, Zazzeroni F, Alesse E. Capece D, et al. J Biomed Biotechnol. 2012;2012:926321. doi: 10.1155/2012/926321. Epub 2012 Feb 12. J Biomed Biotechnol. 2012. PMID: 22500111 Free PMC article. Review.
Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Among authors: d andrea d, capece d. Cancer Cell. 2014 Oct 13;26(4):495-508. doi: 10.1016/j.ccr.2014.07.027. Cancer Cell. 2014. PMID: 25314077 Free PMC article.
Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Among authors: d andrea d, capece d. Cancer Cell. 2014 Dec 8;26(6):938. doi: 10.1016/j.ccell.2014.11.021. Epub 2014 Dec 8. Cancer Cell. 2014. PMID: 28898681 Free PMC article. No abstract available.
NF-κB in the crosshairs: Rethinking an old riddle.
Bennett J, Capece D, Begalli F, Verzella D, D'Andrea D, Tornatore L, Franzoso G. Bennett J, et al. Among authors: d andrea d, capece d. Int J Biochem Cell Biol. 2018 Feb;95:108-112. doi: 10.1016/j.biocel.2017.12.020. Epub 2017 Dec 23. Int J Biochem Cell Biol. 2018. PMID: 29277662 Free PMC article. Review.
GADD45β Loss Ablates Innate Immunosuppression in Cancer.
Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, Forbes SJ, Sica A, Alesse E, Zazzeroni F, Franzoso G. Verzella D, et al. Among authors: d andrea d, capece d. Cancer Res. 2018 Mar 1;78(5):1275-1292. doi: 10.1158/0008-5472.CAN-17-1833. Epub 2017 Dec 26. Cancer Res. 2018. PMID: 29279355 Free PMC article.
Turning an old GADDget into a troublemaker.
Capece D, D'Andrea D, Verzella D, Tornatore L, Begalli F, Bennett J, Zazzeroni F, Franzoso G. Capece D, et al. Among authors: d andrea d. Cell Death Differ. 2018 Mar;25(4):642-644. doi: 10.1038/s41418-018-0087-6. Epub 2018 Mar 6. Cell Death Differ. 2018. PMID: 29511335 Free PMC article. Review. No abstract available.
53 results