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Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas.
Todorova PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, Vemireddy V, Xie XJ, Guida PM, Story MD, Hatanpaa K, Habib AA, Kittler R, Bachoo R, Hromas R, Floyd JR, Burma S. Todorova PK, et al. Among authors: hatanpaa k. Cancer Res. 2019 Jul 15;79(14):3749-3761. doi: 10.1158/0008-5472.CAN-19-0680. Epub 2019 May 14. Cancer Res. 2019. PMID: 31088835 Free PMC article.
RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. Park S, et al. Cancer Res. 2009 May 15;69(10):4107-11. doi: 10.1158/0008-5472.CAN-09-0474. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435890 Free PMC article.
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S. Mukherjee B, et al. Among authors: hatanpaa kj. Cancer Res. 2009 May 15;69(10):4252-9. doi: 10.1158/0008-5472.CAN-08-4853. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435898 Free PMC article.
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
Marin-Valencia I, Cho SK, Rakheja D, Hatanpaa KJ, Kapur P, Mashimo T, Jindal A, Vemireddy V, Good LB, Raisanen J, Sun X, Mickey B, Choi C, Takahashi M, Togao O, Pascual JM, Deberardinis RJ, Maher EA, Malloy CR, Bachoo RM. Marin-Valencia I, et al. Among authors: hatanpaa kj. NMR Biomed. 2012 Oct;25(10):1177-86. doi: 10.1002/nbm.2787. Epub 2012 Mar 1. NMR Biomed. 2012. PMID: 22383401 Free PMC article.
148 results