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Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas.
Todorova PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, Vemireddy V, Xie XJ, Guida PM, Story MD, Hatanpaa K, Habib AA, Kittler R, Bachoo R, Hromas R, Floyd JR, Burma S. Todorova PK, et al. Among authors: story md. Cancer Res. 2019 Jul 15;79(14):3749-3761. doi: 10.1158/0008-5472.CAN-19-0680. Epub 2019 May 14. Cancer Res. 2019. PMID: 31088835 Free PMC article.
RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. Park S, et al. Among authors: story md. Cancer Res. 2009 May 15;69(10):4107-11. doi: 10.1158/0008-5472.CAN-09-0474. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435890 Free PMC article.
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.
Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S. Camacho CV, et al. Among authors: story md. Carcinogenesis. 2010 Oct;31(10):1889-96. doi: 10.1093/carcin/bgq153. Epub 2010 Jul 26. Carcinogenesis. 2010. PMID: 20663777 Free PMC article.
DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy.
Moeller BJ, Yordy JS, Williams MD, Giri U, Raju U, Molkentine DP, Byers LA, Heymach JV, Story MD, Lee JJ, Sturgis EM, Weber RS, Garden AS, Ang KK, Schwartz DL. Moeller BJ, et al. Among authors: story md. Clin Cancer Res. 2011 Apr 1;17(7):2035-43. doi: 10.1158/1078-0432.CCR-10-2641. Epub 2011 Feb 24. Clin Cancer Res. 2011. PMID: 21349997 Free PMC article.
151 results