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Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3.
Heuninck J, Perpiñá Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C. Heuninck J, et al. Among authors: caspar b. Mol Pharmacol. 2019 Dec;96(6):778-793. doi: 10.1124/mol.118.115477. Epub 2019 May 15. Mol Pharmacol. 2019. PMID: 31092552 Free article. Review.
Modulators of CXCR4 and CXCR7/ACKR3 Function.
Adlere I, Caspar B, Arimont M, Dekkers S, Visser K, Stuijt J, de Graaf C, Stocks M, Kellam B, Briddon S, Wijtmans M, de Esch I, Hill S, Leurs R. Adlere I, et al. Among authors: caspar b. Mol Pharmacol. 2019 Dec;96(6):737-752. doi: 10.1124/mol.119.117663. Epub 2019 Sep 23. Mol Pharmacol. 2019. PMID: 31548340 Review.
Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists.
Adlere I, Sun S, Zarca A, Roumen L, Gozelle M, Viciano CP, Caspar B, Arimont M, Bebelman JP, Briddon SJ, Hoffmann C, Hill SJ, Smit MJ, Vischer HF, Wijtmans M, de Graaf C, de Esch IJP, Leurs R. Adlere I, et al. Among authors: caspar b. Eur J Med Chem. 2019 Jan 15;162:631-649. doi: 10.1016/j.ejmech.2018.10.060. Epub 2018 Oct 30. Eur J Med Chem. 2019. PMID: 30476826
The histamine analogue clobenpropit modulates IRF7 phosphorylation and interferon production by targeting CXCR4 in systemic lupus erythematosus models.
Bekaddour N, Smith N, Caspar B, Grinberg S, Giorgiutti S, Rodeschini V, Dupuy S, Leboulanger N, Duffy D, Soulas-Sprauel P, Gies V, Korganow AS, Nisole S, Herbeuval JP. Bekaddour N, et al. Among authors: caspar b. Front Immunol. 2024 Dec 16;15:1490593. doi: 10.3389/fimmu.2024.1490593. eCollection 2024. Front Immunol. 2024. PMID: 39737176 Free PMC article.
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3).
Dekkers S, Comez D, Karsai N, Arimont-Segura M, Canals M, Caspar B, de Graaf C, Kilpatrick LE, Leurs R, Kellam B, Hill SJ, Briddon SJ, Stocks MJ. Dekkers S, et al. Among authors: caspar b. ACS Med Chem Lett. 2023 Dec 8;15(1):143-148. doi: 10.1021/acsmedchemlett.3c00469. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229752 Free PMC article.
13 results