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Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights.
Cheimonidi C, Samara P, Polychronopoulos P, Tsakiri EN, Nikou T, Myrianthopoulos V, Sakellaropoulos T, Zoumpourlis V, Mikros E, Papassideri I, Argyropoulou A, Halabalaki M, Alexopoulos LG, Skaltsounis AL, Tsitsilonis OE, Aligiannis NN, Trougakos IP. Cheimonidi C, et al. Among authors: alexopoulos lg. Redox Biol. 2018 Jun;16:169-178. doi: 10.1016/j.redox.2018.02.015. Epub 2018 Mar 1. Redox Biol. 2018. PMID: 29505920 Free PMC article.
Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling.
Rukhlenko OS, Khorsand F, Krstic A, Rozanc J, Alexopoulos LG, Rauch N, Erickson KE, Hlavacek WS, Posner RG, Gómez-Coca S, Rosta E, Fitzgibbon C, Matallanas D, Rauch J, Kolch W, Kholodenko BN. Rukhlenko OS, et al. Among authors: alexopoulos lg. Cell Syst. 2018 Aug 22;7(2):161-179.e14. doi: 10.1016/j.cels.2018.06.002. Epub 2018 Jul 11. Cell Syst. 2018. PMID: 30007540 Free PMC article.
Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rožanc J, Sakellaropoulos T, Antoranz A, Guttà C, Podder B, Vetma V, Rufo N, Agostinis P, Pliaka V, Sauter T, Kulms D, Rehm M, Alexopoulos LG. Rožanc J, et al. Among authors: alexopoulos lg. Cell Death Differ. 2019 Aug;26(8):1365-1378. doi: 10.1038/s41418-018-0210-8. Epub 2018 Oct 15. Cell Death Differ. 2019. PMID: 30323272 Free PMC article.
Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting.
Rufo N, Korovesis D, Van Eygen S, Derua R, Garg AD, Finotello F, Vara-Perez M, Rožanc J, Dewaele M, de Witte PA, Alexopoulos LG, Janssens S, Sinkkonen L, Sauter T, Verhelst SHL, Agostinis P. Rufo N, et al. Among authors: alexopoulos lg. Cell Death Differ. 2022 Jan;29(1):230-245. doi: 10.1038/s41418-021-00853-5. Epub 2021 Aug 27. Cell Death Differ. 2022. PMID: 34453119 Free PMC article.
104 results