Zhang R - Search Results

1

Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.

Zhang X, Dong G, Li H, Chen W, Li J, Feng C, Gu Z, Zhu F, Zhang R, Li M, Tang W, Liu H, Xu Y. Zhang X, et al. Among authors: zhang r. J Med Chem. 2019 Jun 13;62(11):5579-5593. doi: 10.1021/acs.jmedchem.9b00518. Epub 2019 May 31. J Med Chem. 2019. PMID: 31099559

2

Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.

Zhang R, Li H, Zhang X, Li J, Su H, Lu Q, Dong G, Dou H, Fan C, Gu Z, Mu Q, Tang W, Xu Y, Liu H. Zhang R, et al. Among authors: zhang x. Eur J Med Chem. 2021 Feb 5;211:113004. doi: 10.1016/j.ejmech.2020.113004. Epub 2020 Nov 7. Eur J Med Chem. 2021. PMID: 33218684

3

DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling.

Li H, Li J, Zhang X, Feng C, Fan C, Yang X, Zhang R, Zhu F, Zhou Y, Xu Y, Liu H, Tang W. Li H, et al. Among authors: zhang r, zhang x. Biochem Pharmacol. 2020 Jul;177:113958. doi: 10.1016/j.bcp.2020.113958. Epub 2020 Apr 3. Biochem Pharmacol. 2020. PMID: 32251674

4

Dehydroberberine Analogue Nanoassemblies for Inducing and Self-Reporting Mitochondrial Dysfunction in Tumor Cells.

Zhang R, An R, Gu Z, Sun H, Ye D, Liu H. Zhang R, et al. ACS Appl Bio Mater. 2021 Mar 15;4(3):2033-2043. doi: 10.1021/acsabm.0c00747. Epub 2020 Aug 18. ACS Appl Bio Mater. 2021. PMID: 35014329

5

Rhodium(III)-Catalyzed [4+2] Annulation via C-H Activation: Synthesis of Multi-Substituted Naphthalenone Sulfoxonium Ylides.

Song X, Han X, Zhang R, Liu H, Wang J. Song X, et al. Among authors: zhang r. Molecules. 2019 May 16;24(10):1884. doi: 10.3390/molecules24101884. Molecules. 2019. PMID: 31100874 Free PMC article.

6

Estimation of relative contribution of "mobile phycobilisome" and "energy spillover" in the light-dark induced state transition in Spirulina platensis.

Zhang R, Li H, Xie J, Zhao J. Zhang R, et al. Photosynth Res. 2007 Nov-Dec;94(2-3):315-20. doi: 10.1007/s11120-007-9272-z. Epub 2007 Oct 20. Photosynth Res. 2007. PMID: 17952696

7

Lead optimization generates selenium-containing miconazole CYP51 inhibitors with improved pharmacological profile for the treatment of fungal infections.

Xu H, Yan ZZ, Guo MB, An R, Wang X, Zhang R, Mou YH, Hou Z, Guo C. Xu H, et al. Among authors: zhang r. Eur J Med Chem. 2021 Apr 15;216:113337. doi: 10.1016/j.ejmech.2021.113337. Epub 2021 Mar 2. Eur J Med Chem. 2021. PMID: 33713977

8

Regio-selective and stereo-selective hydrosilylation of internal alkynes catalyzed by ruthenium complexes.

Dai W, Wu X, Li C, Zhang R, Wang J, Liu H. Dai W, et al. Among authors: zhang r. RSC Adv. 2018 Aug 7;8(49):28261-28265. doi: 10.1039/c8ra04083d. eCollection 2018 Aug 2. RSC Adv. 2018. PMID: 35542735 Free PMC article.

9

Relationship between periodontitis and microangiopathy in type 2 diabetes mellitus: a meta-analysis.

Zhang X, Wang M, Wang X, Qu H, Zhang R, Gu J, Wu Y, Ni T, Tang W, Li Q. Zhang X, et al. Among authors: zhang r. J Periodontal Res. 2021 Dec;56(6):1019-1027. doi: 10.1111/jre.12916. Epub 2021 Jul 13. J Periodontal Res. 2021. PMID: 34254680 Review.

10

Discovery of Novel Pterostilbene-Based Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors with Inflammatory Activity for Colitis.

Chen LZ, Zhang XX, Liu MM, Wu J, Ma D, Diao LZ, Li Q, Huang YS, Zhang R, Ruan BF, Liu XH. Chen LZ, et al. Among authors: zhang r, zhang xx. J Med Chem. 2021 Sep 23;64(18):13633-13657. doi: 10.1021/acs.jmedchem.1c01007. Epub 2021 Sep 10. J Med Chem. 2021. PMID: 34506712

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