Lin X - Search Results

1

Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination.

Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S. Jiang W, et al. Among authors: lin x. J Immunol. 2019 Jul 1;203(1):178-187. doi: 10.4049/jimmunol.1801657. Epub 2019 May 17. J Immunol. 2019. PMID: 31101667 Free PMC article.

2

CtIP is essential for early B cell proliferation and development in mice.

Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S. Liu X, et al. Among authors: lin x. J Exp Med. 2019 Jul 1;216(7):1648-1663. doi: 10.1084/jem.20181139. Epub 2019 May 16. J Exp Med. 2019. PMID: 31097467 Free PMC article.

3

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo.

Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S. Shao Z, et al. Among authors: lin x. Nucleic Acids Res. 2020 Sep 25;48(17):9694-9709. doi: 10.1093/nar/gkaa718. Nucleic Acids Res. 2020. PMID: 32890402 Free PMC article.

4

FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis.

Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S. Milanovic M, et al. Among authors: lin x. J Immunol. 2021 Mar 15;206(6):1228-1239. doi: 10.4049/jimmunol.2000967. Epub 2021 Feb 3. J Immunol. 2021. PMID: 33536256 Free PMC article.

5

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites.

Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S. Lin X, et al. Nucleic Acids Res. 2022 Apr 22;50(7):3958-3973. doi: 10.1093/nar/gkac188. Nucleic Acids Res. 2022. PMID: 35349716 Free PMC article.

6

Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging.

Zhang H, Lin X, Zha S. Zhang H, et al. Among authors: lin x. Biochem Soc Trans. 2022 Aug 31;50(4):1169-1177. doi: 10.1042/BST20220366. Biochem Soc Trans. 2022. PMID: 35959996

7

Clinical PARP inhibitors allosterically induce PARP2 retention on DNA.

Langelier MF, Lin X, Zha S, Pascal JM. Langelier MF, et al. Among authors: lin x. Sci Adv. 2023 Mar 24;9(12):eadf7175. doi: 10.1126/sciadv.adf7175. Epub 2023 Mar 24. Sci Adv. 2023. PMID: 36961901 Free PMC article.

8

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner.

Shao Z, Lee BJ, Zhang H, Lin X, Li C, Jiang W, Chirathivat N, Gershik S, Shen MM, Baer R, Zha S. Shao Z, et al. Among authors: lin x. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2301972120. doi: 10.1073/pnas.2301972120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487079 Free PMC article.

9

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Lin X, et al. bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584665. doi: 10.1101/2024.03.12.584665. bioRxiv. 2024. Update in: Mol Cell. 2024 Oct 17;84(20):3916-3931.e7. doi: 10.1016/j.molcel.2024.09.020 PMID: 38559022 Free PMC article. Updated. Preprint.

10

XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites.

Lin X, Leung KSK, Wolfe KF, Lee BJ, Zha S. Lin X, et al. bioRxiv [Preprint]. 2024 May 17:2024.05.14.594230. doi: 10.1101/2024.05.14.594230. bioRxiv. 2024. PMID: 38798615 Free PMC article. Preprint.

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