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Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Among authors: giaco l. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations.
Bodini M, Ronchini C, Giacò L, Russo A, Melloni GE, Luzi L, Sardella D, Volorio S, Hasan SK, Ottone T, Lavorgna S, Lo-Coco F, Candoni A, Fanin R, Toffoletti E, Iacobucci I, Martinelli G, Cignetti A, Tarella C, Bernard L, Pelicci PG, Riva L. Bodini M, et al. Among authors: giaco l. Blood. 2015 Jan 22;125(4):600-5. doi: 10.1182/blood-2014-05-576157. Epub 2014 Dec 12. Blood. 2015. PMID: 25499761 Free PMC article. Review.
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.
Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L. Bossi D, et al. Among authors: giaco l. Cancer Discov. 2016 Jun;6(6):650-63. doi: 10.1158/2159-8290.CD-15-1200. Epub 2016 May 13. Cancer Discov. 2016. PMID: 27179036
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.
Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F. Sanarico AG, et al. Among authors: giaco l. Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6. Leukemia. 2018. PMID: 29209041 Free PMC article.
A Computational Framework for Comprehensive Genomic Profiling in Solid Cancers: The Analytical Performance of a High-Throughput Assay for Small and Copy Number Variants.
Giacò L, Palluzzi F, Guido D, Nero C, Giacomini F, Duranti S, Bria E, Tortora G, Cenci T, Martini M, De Paolis E, Onori ME, De Bonis M, Normanno N, Scambia G, Minucci A. Giacò L, et al. Cancers (Basel). 2022 Dec 13;14(24):6152. doi: 10.3390/cancers14246152. Cancers (Basel). 2022. PMID: 36551638 Free PMC article.
The impact of the COVID-19 pandemic on oncological disease extent at FDG PET/CT staging: the ONCOVIPET study.
Caldarella C, Cocciolillo F, Taralli S, Lorusso M, Scolozzi V, Pizzuto DA, Calcagni ML, Rufini V, Guido D, Palluzzi F, Giacò L, Giordano A, Leccisotti L. Caldarella C, et al. Among authors: giaco l. Eur J Nucl Med Mol Imaging. 2022 Apr;49(5):1623-1629. doi: 10.1007/s00259-021-05629-0. Epub 2021 Dec 8. Eur J Nucl Med Mol Imaging. 2022. PMID: 34877609 Free PMC article.
Identification of a novel gene signature predicting response to first-line chemotherapy in BRCA wild-type high-grade serous ovarian cancer patients.
Buttarelli M, Ciucci A, Palluzzi F, Raspaglio G, Marchetti C, Perrone E, Minucci A, Giacò L, Fagotti A, Scambia G, Gallo D. Buttarelli M, et al. Among authors: giaco l. J Exp Clin Cancer Res. 2022 Feb 4;41(1):50. doi: 10.1186/s13046-022-02265-w. J Exp Clin Cancer Res. 2022. PMID: 35120576 Free PMC article.
Evaluating the Risk of Inguinal Lymph Node Metastases before Surgery Using the Morphonode Predictive Model: A Prospective Diagnostic Study in Vulvar Cancer Patients.
Fragomeni SM, Moro F, Palluzzi F, Mascilini F, Rufini V, Collarino A, Inzani F, Giacò L, Scambia G, Testa AC, Garganese G. Fragomeni SM, et al. Among authors: giaco l. Cancers (Basel). 2023 Feb 9;15(4):1121. doi: 10.3390/cancers15041121. Cancers (Basel). 2023. PMID: 36831462 Free PMC article.
28 results