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Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Among authors: luzi l. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
Evolution of Shc functions from nematode to human.
Luzi L, Confalonieri S, Di Fiore PP, Pelicci PG. Luzi L, et al. Curr Opin Genet Dev. 2000 Dec;10(6):668-74. doi: 10.1016/s0959-437x(00)00146-5. Curr Opin Genet Dev. 2000. PMID: 11088019 Review.
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair.
Alcalay M, Meani N, Gelmetti V, Fantozzi A, Fagioli M, Orleth A, Riganelli D, Sebastiani C, Cappelli E, Casciari C, Sciurpi MT, Mariano AR, Minardi SP, Luzi L, Muller H, Di Fiore PP, Frosina G, Pelicci PG. Alcalay M, et al. Among authors: luzi l. J Clin Invest. 2003 Dec;112(11):1751-61. doi: 10.1172/JCI17595. J Clin Invest. 2003. PMID: 14660751 Free PMC article.
307 results