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219 results

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Page 1
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Among authors: melloni g. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.
Riva L, Ronchini C, Bodini M, Lo-Coco F, Lavorgna S, Ottone T, Martinelli G, Iacobucci I, Tarella C, Cignetti A, Volorio S, Bernard L, Russo A, Melloni GE, Luzi L, Alcalay M, Dellino GI, Pelicci PG. Riva L, et al. Among authors: melloni ge. Blood Cancer J. 2013 Sep 13;3(9):e147. doi: 10.1038/bcj.2013.46. Blood Cancer J. 2013. PMID: 24036946 Free PMC article. No abstract available.
The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations.
Bodini M, Ronchini C, Giacò L, Russo A, Melloni GE, Luzi L, Sardella D, Volorio S, Hasan SK, Ottone T, Lavorgna S, Lo-Coco F, Candoni A, Fanin R, Toffoletti E, Iacobucci I, Martinelli G, Cignetti A, Tarella C, Bernard L, Pelicci PG, Riva L. Bodini M, et al. Among authors: melloni ge. Blood. 2015 Jan 22;125(4):600-5. doi: 10.1182/blood-2014-05-576157. Epub 2014 Dec 12. Blood. 2015. PMID: 25499761 Free PMC article. Review.
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.
Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L. Bossi D, et al. Among authors: melloni g. Cancer Discov. 2016 Jun;6(6):650-63. doi: 10.1158/2159-8290.CD-15-1200. Epub 2016 May 13. Cancer Discov. 2016. PMID: 27179036
Mutations targeting the coagulation pathway are enriched in brain metastases.
Richichi C, Fornasari L, Melloni GEM, Brescia P, Patanè M, Del Bene M, Mustafa DAM, Kros JM, Pollo B, Pruneri G, Sciandivasci A, Munzone E, DiMeco F, Pelicci PG, Riva L, Pelicci G. Richichi C, et al. Among authors: melloni gem. Sci Rep. 2017 Jul 26;7(1):6573. doi: 10.1038/s41598-017-06811-x. Sci Rep. 2017. PMID: 28747664 Free PMC article.
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.
Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F. Sanarico AG, et al. Among authors: melloni gem. Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6. Leukemia. 2018. PMID: 29209041 Free PMC article.
p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.
Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabò A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG. Santoro A, et al. Among authors: melloni g. Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071. Cell Rep. 2019. PMID: 30650356 Free PMC article.
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.
Riva L, Ronchini C, Bodini M, Lo-Coco F, Lavorgna S, Ottone T, Martinelli G, Iacobucci I, Tarella C, Cignetti A, Volorio S, Bernard L, Russo A, Melloni GE, Luzi L, Alcalay M, Dellino GI, Pelicci PG. Riva L, et al. Among authors: melloni ge. Blood Cancer J. 2014 Mar 21;4(3):e195. doi: 10.1038/bcj.2014.19. Blood Cancer J. 2014. PMID: 24658373 Free PMC article. No abstract available.
219 results