Tuschl T - Search Results

1

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Among authors: tuschl t. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.

2

A pancreatic islet-specific microRNA regulates insulin secretion.

Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M. Poy MN, et al. Among authors: tuschl t. Nature. 2004 Nov 11;432(7014):226-30. doi: 10.1038/nature03076. Nature. 2004. PMID: 15538371

3

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.

Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Ma JB, et al. Among authors: tuschl t. Nature. 2005 Mar 31;434(7033):666-70. doi: 10.1038/nature03514. Nature. 2005. PMID: 15800629 Free PMC article.

4

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.

Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter Z, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: tuschl t. Mol Cell. 2005 Aug 5;19(3):405-19. doi: 10.1016/j.molcel.2005.07.011. Mol Cell. 2005. PMID: 16061186 Free PMC article.

5

A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.

Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: tuschl t. Structure. 2006 Oct;14(10):1557-65. doi: 10.1016/j.str.2006.08.009. Structure. 2006. PMID: 17027504 Free PMC article.

6

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.

Zhang X, Yuan YR, Pei Y, Lin SS, Tuschl T, Patel DJ, Chua NH. Zhang X, et al. Among authors: tuschl t. Genes Dev. 2006 Dec 1;20(23):3255-68. doi: 10.1101/gad.1495506. Genes Dev. 2006. PMID: 17158744 Free PMC article.

7

Structural biology of RNA silencing and its functional implications.

Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Patel DJ, et al. Among authors: tuschl t. Cold Spring Harb Symp Quant Biol. 2006;71:81-93. doi: 10.1101/sqb.2006.71.053. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381284 Free PMC article. Review.

8

Structure of the guide-strand-containing argonaute silencing complex.

Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Wang Y, et al. Among authors: tuschl t. Nature. 2008 Nov 13;456(7219):209-13. doi: 10.1038/nature07315. Epub 2008 Aug 27. Nature. 2008. PMID: 18754009 Free PMC article.

9

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.

Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ. Wang Y, et al. Among authors: tuschl t. Nature. 2008 Dec 18;456(7224):921-6. doi: 10.1038/nature07666. Nature. 2008. PMID: 19092929 Free PMC article.

10

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.

Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Wang Y, et al. Among authors: tuschl t. Nature. 2009 Oct 8;461(7265):754-61. doi: 10.1038/nature08434. Nature. 2009. PMID: 19812667 Free PMC article.

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