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Page 1
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure.
Mossner M, Jann JC, Wittig J, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Boch T, Metzgeroth G, Röhl H, Witt SH, Dukal H, Klein C, Schmitt S, Gelß P, Platzbecker U, Balaian E, Fabarius A, Blum H, Schulze TJ, Meggendorfer M, Haferlach C, Trumpp A, Hofmann WK, Medyouf H, Nowak D. Mossner M, et al. Among authors: palme i. Blood. 2016 Sep 1;128(9):1246-59. doi: 10.1182/blood-2015-11-679167. Epub 2016 Jun 6. Blood. 2016. PMID: 27268087 Free article.
Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA.
Jann JC, Nowak D, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Fabarius A, Platzbecker U, Giagounidis A, Götze K, Letsch A, Haase D, Schlenk R, Bug G, Lübbert M, Ganser A, Germing U, Haferlach C, Hofmann WK, Mossner M. Jann JC, et al. Among authors: palme i. J Med Genet. 2017 Sep;54(9):640-650. doi: 10.1136/jmedgenet-2017-104528. Epub 2017 Jun 9. J Med Genet. 2017. PMID: 28600436 Free PMC article.
Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations.
Flach J, Jann JC, Knaflic A, Riabov V, Streuer A, Altrock E, Xu Q, Schmitt N, Obländer J, Nowak V, Danner J, Mehralivand A, Hofmann F, Palme I, Jawhar A, Wuchter P, Metzgeroth G, Nolte F, Hofmann WK, Nowak D. Flach J, et al. Among authors: palme i. Haematologica. 2021 Nov 1;106(11):2906-2917. doi: 10.3324/haematol.2020.254193. Haematologica. 2021. PMID: 33054116 Free PMC article.
High erythroferrone expression in CD71+ erythroid progenitors predicts superior survival in myelodysplastic syndromes.
Riabov V, Mossner M, Stöhr A, Jann JC, Streuer A, Schmitt N, Knaflic A, Nowak V, Weimer N, Obländer J, Palme I, Schumann C, Baldus CD, Schulze TJ, Wuchter P, Röhl H, Jawhar A, Weiss C, Boch T, Metzgeroth G, Neumann M, Hofmann WK, Nolte F, Nowak D. Riabov V, et al. Among authors: palme i. Br J Haematol. 2021 Mar;192(5):879-891. doi: 10.1111/bjh.17314. Epub 2021 Jan 24. Br J Haematol. 2021. PMID: 33486765
Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes.
Schmitt N, Jann JC, Altrock E, Flach J, Danner J, Uhlig S, Streuer A, Knaflic A, Riabov V, Xu Q, Mehralivand A, Palme I, Nowak V, Obländer J, Weimer N, Haselmann V, Jawhar A, Darwich A, Weis CA, Marx A, Steiner L, Jawhar M, Metzgeroth G, Boch T, Nolte F, Hofmann WK, Nowak D. Schmitt N, et al. Among authors: palme i. Leukemia. 2022 Jan;36(1):236-247. doi: 10.1038/s41375-021-01327-w. Epub 2021 Jun 25. Leukemia. 2022. PMID: 34172896 Free PMC article.
Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo.
Jann JC, Mossner M, Riabov V, Altrock E, Schmitt N, Flach J, Xu Q, Nowak V, Obländer J, Palme I, Weimer N, Streuer A, Jawhar A, Darwich A, Jawhar M, Metzgeroth G, Nolte F, Hofmann WK, Nowak D. Jann JC, et al. Among authors: palme i. Nat Commun. 2021 Oct 25;12(1):6170. doi: 10.1038/s41467-021-26424-3. Nat Commun. 2021. PMID: 34697318 Free PMC article.
Humanized three-dimensional scaffold xenotransplantation models for myelodysplastic syndromes.
Altrock E, Sens-Albert C, Jann JC, Flach J, Riabov V, Schmitt N, Xu Q, Mehralivand A, Hecht A, Steiner L, Streuer A, Nowak V, Obländer J, Weimer N, Palme I, Jawhar A, Weis CA, Weyer V, Nolte F, Jawhar M, Metzgeroth G, Marx A, Groden C, Hofmann WK, Nowak D. Altrock E, et al. Among authors: palme i. Exp Hematol. 2022 Mar;107:38-50. doi: 10.1016/j.exphem.2021.12.395. Epub 2021 Dec 22. Exp Hematol. 2022. PMID: 34952140 Free article.
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