Haddish-Berhane N - Search Results

1

Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®.

Betts A, Haddish-Berhane N, Shah DK, van der Graaf PH, Barletta F, King L, Clark T, Kamperschroer C, Root A, Hooper A, Chen X. Betts A, et al. AAPS J. 2019 Jun 4;21(4):73. doi: 10.1208/s12248-019-0348-4. AAPS J. 2019. PMID: 31165304 Free PMC article.

2

A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART^®.

Betts A, Haddish-Berhane N, Shah DK, van der Graaf PH, Barletta F, King L, Clark T, Kamperschroer C, Root A, Hooper A, Chen X. Betts A, et al. AAPS J. 2019 May 22;21(4):66. doi: 10.1208/s12248-019-0332-z. AAPS J. 2019. PMID: 31119428 Free PMC article.

3

Mechanistic Projection of First-in-Human Dose for Bispecific Immunomodulatory P-Cadherin LP-DART: An Integrated PK/PD Modeling Approach.

Chen X, Haddish-Berhane N, Moore P, Clark T, Yang Y, Li H, Xuan D, Barton HA, Betts AM, Barletta F. Chen X, et al. Clin Pharmacol Ther. 2016 Sep;100(3):232-41. doi: 10.1002/cpt.393. Epub 2016 Jul 21. Clin Pharmacol Ther. 2016. PMID: 27170541

4

Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin.

Betts AM, Haddish-Berhane N, Tolsma J, Jasper P, King LE, Sun Y, Chakrapani S, Shor B, Boni J, Johnson TR. Betts AM, et al. AAPS J. 2016 Sep;18(5):1101-1116. doi: 10.1208/s12248-016-9929-7. Epub 2016 May 19. AAPS J. 2016. PMID: 27198897

5

A priori prediction of tumor payload concentrations: preclinical case study with an auristatin-based anti-5T4 antibody-drug conjugate.

Shah DK, King LE, Han X, Wentland JA, Zhang Y, Lucas J, Haddish-Berhane N, Betts A, Leal M. Shah DK, et al. AAPS J. 2014 May;16(3):452-63. doi: 10.1208/s12248-014-9576-9. Epub 2014 Mar 1. AAPS J. 2014. PMID: 24578215 Free PMC article.

6

Establishing in vitro-in vivo correlation for antibody drug conjugate efficacy: a PK/PD modeling approach.

Shah DK, Loganzo F, Haddish-Berhane N, Musto S, Wald HS, Barletta F, Lucas J, Clark T, Hansel S, Betts A. Shah DK, et al. J Pharmacokinet Pharmacodyn. 2018 Apr;45(2):339-349. doi: 10.1007/s10928-018-9577-x. Epub 2018 Feb 8. J Pharmacokinet Pharmacodyn. 2018. PMID: 29423862

7

A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice.

Fisher TS, Hooper AT, Lucas J, Clark TH, Rohner AK, Peano B, Elliott MW, Tsaparikos K, Wang H, Golas J, Gavriil M, Haddish-Berhane N, Tchistiakova L, Gerber HP, Root AR, May C. Fisher TS, et al. Cancer Immunol Immunother. 2018 Feb;67(2):247-259. doi: 10.1007/s00262-017-2081-0. Epub 2017 Oct 24. Cancer Immunol Immunother. 2018. PMID: 29067496 Free PMC article.

8

Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin.

Shah DK, Haddish-Berhane N, Betts A. Shah DK, et al. J Pharmacokinet Pharmacodyn. 2012 Dec;39(6):643-59. doi: 10.1007/s10928-012-9276-y. Epub 2012 Nov 15. J Pharmacokinet Pharmacodyn. 2012. PMID: 23151991

9

On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach.

Haddish-Berhane N, Shah DK, Ma D, Leal M, Gerber HP, Sapra P, Barton HA, Betts AM. Haddish-Berhane N, et al. J Pharmacokinet Pharmacodyn. 2013 Oct;40(5):557-71. doi: 10.1007/s10928-013-9329-x. Epub 2013 Aug 10. J Pharmacokinet Pharmacodyn. 2013. PMID: 23933716

10

Antibody-drug conjugates: an emerging modality for the treatment of cancer.

Leal M, Sapra P, Hurvitz SA, Senter P, Wahl A, Schutten M, Shah DK, Haddish-Berhane N, Kabbarah O. Leal M, et al. Ann N Y Acad Sci. 2014 Aug;1321:41-54. doi: 10.1111/nyas.12499. Ann N Y Acad Sci. 2014. PMID: 25123209 Review.

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