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Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
Wang R, Song S, Harada K, Ghazanfari Amlashi F, Badgwell B, Pizzi MP, Xu Y, Zhao W, Dong X, Jin J, Wang Y, Scott A, Ma L, Huo L, Vicente D, Blum Murphy M, Shanbhag N, Tatlonghari G, Thomas I, Rogers J, Kobayashi M, Vykoukal J, Estrella JS, Roy-Chowdhuri S, Han G, Zhang S, Mao X, Song X, Zhang J, Gu J, Johnson RL, Calin GA, Peng G, Lee JS, Hanash SM, Futreal A, Wang Z, Wang L, Ajani JA. Wang R, et al. Among authors: johnson rl. Gut. 2020 Jan;69(1):18-31. doi: 10.1136/gutjnl-2018-318070. Epub 2019 Jun 6. Gut. 2020. PMID: 31171626 Free PMC article.
ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients.
Ajani JA, Wang X, Song S, Suzuki A, Taketa T, Sudo K, Wadhwa R, Hofstetter WL, Komaki R, Maru DM, Lee JH, Bhutani MS, Weston B, Baladandayuthapani V, Yao Y, Honjo S, Scott AW, Skinner HD, Johnson RL, Berry D. Ajani JA, et al. Among authors: johnson rl. Mol Oncol. 2014 Feb;8(1):142-9. doi: 10.1016/j.molonc.2013.10.007. Epub 2013 Oct 28. Mol Oncol. 2014. PMID: 24210755 Free PMC article.
Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties.
Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Stroehlein JR, Martin JF, Hung MC, Johnson RL. Song S, et al. Among authors: johnson rl. Cancer Res. 2014 Aug 1;74(15):4170-82. doi: 10.1158/0008-5472.CAN-13-3569. Epub 2014 Jun 6. Cancer Res. 2014. PMID: 24906622 Free PMC article.
Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors.
Ajani JA, Estrella JS, Chen Q, Correa AM, Ma L, Scott AW, Jin J, Liu B, Xie M, Sudo K, Shiozaki H, Badgwell B, Weston B, Lee JH, Bhutani MS, Onodera H, Suzuki K, Suzuki A, Ding S, Hofstetter WL, Johnson RL, Bresalier RS, Song S. Ajani JA, et al. Among authors: johnson rl. Br J Cancer. 2018 Jan;118(1):52-61. doi: 10.1038/bjc.2017.388. Epub 2017 Nov 14. Br J Cancer. 2018. PMID: 29136404 Free PMC article.
1,213 results