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Page 1
Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.
Fischer CG, Beleva Guthrie V, Braxton AM, Zheng L, Wang P, Song Q, Griffin JF, Chianchiano PE, Hosoda W, Niknafs N, Springer S, Dal Molin M, Masica D, Scharpf RB, Thompson ED, He J, Wolfgang CL, Hruban RH, Roberts NJ, Lennon AM, Jiao Y, Karchin R, Wood LD. Fischer CG, et al. Among authors: chianchiano pe. Gastroenterology. 2019 Oct;157(4):1123-1137.e22. doi: 10.1053/j.gastro.2019.06.001. Epub 2019 Jun 5. Gastroenterology. 2019. PMID: 31175866 Free PMC article.
IPMNs with co-occurring invasive cancers: neighbours but not always relatives.
Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD. Felsenstein M, et al. Gut. 2018 Sep;67(9):1652-1662. doi: 10.1136/gutjnl-2017-315062. Epub 2018 Mar 2. Gut. 2018. PMID: 29500184 Free PMC article.
Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.
Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD. Kuboki Y, et al. J Pathol. 2019 Mar;247(3):347-356. doi: 10.1002/path.5194. Epub 2019 Jan 16. J Pathol. 2019. PMID: 30430578 Free PMC article.
The Impact of Clinical and Pathological Features on Intraductal Papillary Mucinous Neoplasm Recurrence After Surgical Resection: Long-Term Follow-Up Analysis.
Pflüger MJ, Griffin JF, Hackeng WM, Kawamoto S, Yu J, Chianchiano P, Shin E, Lionheart G, Tsai HL, Wang H, Rezaee N, Burkhart RA, Cameron JL, Thompson ED, Wolfgang CL, He J, Brosens LAA, Wood LD. Pflüger MJ, et al. Ann Surg. 2022 Jun 1;275(6):1165-1174. doi: 10.1097/SLA.0000000000004427. Epub 2020 Nov 17. Ann Surg. 2022. PMID: 33214420 Free PMC article.
Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4.
Hosoda W, Chianchiano P, Griffin JF, Pittman ME, Brosens LA, Noë M, Yu J, Shindo K, Suenaga M, Rezaee N, Yonescu R, Ning Y, Albores-Saavedra J, Yoshizawa N, Harada K, Yoshizawa A, Hanada K, Yonehara S, Shimizu M, Uehara T, Samra JS, Gill AJ, Wolfgang CL, Goggins MG, Hruban RH, Wood LD. Hosoda W, et al. J Pathol. 2017 May;242(1):16-23. doi: 10.1002/path.4884. Epub 2017 Mar 30. J Pathol. 2017. PMID: 28188630 Free PMC article.
Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
Huang W, Navarro-Serer B, Jeong YJ, Chianchiano P, Xia L, Luchini C, Veronese N, Dowiak C, Ng T, Trujillo MA, Huang B, Pflüger MJ, Macgregor-Das AM, Lionheart G, Jones D, Fujikura K, Nguyen-Ngoc KV, Neumann NM, Groot VP, Hasanain A, van Oosten AF, Fischer SE, Gallinger S, Singhi AD, Zureikat AH, Brand RE, Gaida MM, Heinrich S, Burkhart RA, He J, Wolfgang CL, Goggins MG, Thompson ED, Roberts NJ, Ewald AJ, Wood LD. Huang W, et al. Cancer Res. 2020 Jul 1;80(13):2804-2817. doi: 10.1158/0008-5472.CAN-19-1523. Epub 2020 May 6. Cancer Res. 2020. PMID: 32376602 Free PMC article.
Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups With Differing Risks of Liver Metastases.
Pea A, Yu J, Marchionni L, Noe M, Luchini C, Pulvirenti A, de Wilde RF, Brosens LA, Rezaee N, Javed A, Chianchiano P, Gobbo S, Regi P, Salvia R, Bassi C, He J, Weiss MJ, Cameron JL, Offerhaus GJA, Hruban RH, Lawlor RT, Scarpa A, Heaphy CM, Wood LD, Wolfgang CL. Pea A, et al. Ann Surg. 2020 Mar;271(3):566-573. doi: 10.1097/SLA.0000000000003022. Ann Surg. 2020. PMID: 30339629 Free PMC article.
Biphenotypic Differentiation of Pancreatic Cancer in 3-Dimensional Culture.
Matsushita Y, Smith B, Delannoy M, Trujillo MA, Chianchiano P, McMillan R, Kamiyama H, Liang H, Thompson ED, Hruban RH, Matsui W, Wood LD, Roberts NJ, Eshleman JR. Matsushita Y, et al. Pancreas. 2019 Oct;48(9):1225-1231. doi: 10.1097/MPA.0000000000001390. Pancreas. 2019. PMID: 31593010 Free PMC article.
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