Kaufman RJ - Search Results

1

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.

Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ. Jang I, et al. Among authors: kaufman rj. Elife. 2019 Jun 11;8:e44528. doi: 10.7554/eLife.44528. Elife. 2019. PMID: 31184304 Free PMC article.

2

Translational control is required for the unfolded protein response and in vivo glucose homeostasis.

Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Mol Cell. 2001 Jun;7(6):1165-76. doi: 10.1016/s1097-2765(01)00265-9. Mol Cell. 2001. PMID: 11430820 Free article.

3

The unfolded protein response in nutrient sensing and differentiation.

Kaufman RJ, Scheuner D, Schröder M, Shen X, Lee K, Liu CY, Arnold SM. Kaufman RJ, et al. Nat Rev Mol Cell Biol. 2002 Jun;3(6):411-21. doi: 10.1038/nrm829. Nat Rev Mol Cell Biol. 2002. PMID: 12042763 Review.

4

The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.

Scheuner D, Gromeier M, Davies MV, Dorner AJ, Song B, Patel RV, Wimmer EJ, McLendon RE, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Virology. 2003 Dec 20;317(2):263-74. doi: 10.1016/j.virol.2003.08.010. Virology. 2003. PMID: 14698665 Free article.

5

Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis.

Wu S, Tan M, Hu Y, Wang JL, Scheuner D, Kaufman RJ. Wu S, et al. Among authors: kaufman rj. J Biol Chem. 2004 Aug 13;279(33):34898-902. doi: 10.1074/jbc.M405616200. Epub 2004 Jun 7. J Biol Chem. 2004. PMID: 15184376 Free article.

6

Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure.

McEwen E, Kedersha N, Song B, Scheuner D, Gilks N, Han A, Chen JJ, Anderson P, Kaufman RJ. McEwen E, et al. Among authors: kaufman rj. J Biol Chem. 2005 Apr 29;280(17):16925-33. doi: 10.1074/jbc.M412882200. Epub 2005 Jan 31. J Biol Chem. 2005. PMID: 15684421 Free article.

7

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. Zhang K, et al. Among authors: kaufman rj. J Clin Invest. 2005 Feb;115(2):268-81. doi: 10.1172/JCI21848. J Clin Invest. 2005. PMID: 15690081 Free PMC article.

8

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis.

Scheuner D, Vander Mierde D, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Nat Med. 2005 Jul;11(7):757-64. doi: 10.1038/nm1259. Epub 2005 Jun 26. Nat Med. 2005. PMID: 15980866

9

Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis.

Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, Nilsson A, Karin M, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. J Biol Chem. 2006 Jul 28;281(30):21458-21468. doi: 10.1074/jbc.M603784200. Epub 2006 May 22. J Biol Chem. 2006. PMID: 16717090 Free article.

10

The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes.

Scheuner D, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. Endocr Rev. 2008 May;29(3):317-33. doi: 10.1210/er.2007-0039. Epub 2008 Apr 24. Endocr Rev. 2008. PMID: 18436705 Free PMC article. Review.

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