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Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V. Gothe HJ, et al. Among authors: takeda s. Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12. Mol Cell. 2019. PMID: 31202576 Free article.
Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.
Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H. Keka IS, et al. Among authors: takeda s. Nucleic Acids Res. 2015 Jul 27;43(13):6359-72. doi: 10.1093/nar/gkv621. Epub 2015 Jun 18. Nucleic Acids Res. 2015. PMID: 26089390 Free PMC article.
Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines.
Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H. Hoa NN, et al. Among authors: takeda s. Genes Cells. 2015 Dec;20(12):1059-76. doi: 10.1111/gtc.12310. Epub 2015 Nov 2. Genes Cells. 2015. PMID: 26525166 Free PMC article.
Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia.
Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A. Tada K, et al. Among authors: takeda s. Sci Adv. 2015 Apr 24;1(3):e1400203. doi: 10.1126/sciadv.1400203. eCollection 2015 Apr. Sci Adv. 2015. PMID: 26601161 Free PMC article.
3,821 results