Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair.
Fergie N, Todd N, McClements L, McAuley D, O'Kane C, Krasnodembskaya A.
Fergie N, et al. Among authors: krasnodembskaya a.
FASEB J. 2019 Apr;33(4):5585-5598. doi: 10.1096/fj.201802056R. Epub 2019 Jan 16.
FASEB J. 2019.
PMID: 30649987
Free PMC article.
Mesenchymal stem cells (MSCs) are a promising therapeutic candidate currently in early-phase clinical trials. The effects of HCA on the alveolar epithelium and capillary endothelium are not well established. ...-Fergie, N., Todd, N., McClements, L., McAuley, D., O'Kane, C. …
Mesenchymal stem cells (MSCs) are a promising therapeutic candidate currently in early-phase clinical trials. The effects of HCA on t …