Labesse G - Search Results

1

A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor.

Loeuillet C, Touquet B, Guichou JF, Labesse G, Sereno D. Loeuillet C, et al. Among authors: labesse g. Int J Mol Sci. 2019 Jun 18;20(12):2973. doi: 10.3390/ijms20122973. Int J Mol Sci. 2019. PMID: 31216674 Free PMC article.

2

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.

Gedeon A, Ayoub N, Brûlé S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H. Gedeon A, et al. Among authors: labesse g. Protein Sci. 2023 Aug;32(8):e4703. doi: 10.1002/pro.4703. Protein Sci. 2023. PMID: 37338125 Free PMC article.

3

Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events.

Lacroix B, Vigneron S, Labbé JC, Pintard L, Lionne C, Labesse G, Castro A, Lorca T. Lacroix B, et al. Among authors: labesse g. EMBO J. 2024 Mar;43(6):993-1014. doi: 10.1038/s44318-024-00054-z. Epub 2024 Feb 20. EMBO J. 2024. PMID: 38378890 Free PMC article.

4

The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.

Gazanion E, Garcia D, Silvestre R, Gérard C, Guichou JF, Labesse G, Seveno M, Cordeiro-Da-Silva A, Ouaissi A, Sereno D, Vergnes B. Gazanion E, et al. Among authors: labesse g. Mol Microbiol. 2011 Oct;82(1):21-38. doi: 10.1111/j.1365-2958.2011.07799.x. Epub 2011 Sep 1. Mol Microbiol. 2011. PMID: 21819459 Free article.

5

In-plate protein crystallization, in situ ligand soaking and X-ray diffraction.

le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL, Labesse G. le Maire A, et al. Among authors: labesse g. Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):747-55. doi: 10.1107/S0907444911023249. Epub 2011 Aug 9. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21904027

6

Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.

Gelin M, Delfosse V, Allemand F, Hoh F, Sallaz-Damaz Y, Pirocchi M, Bourguet W, Ferrer JL, Labesse G, Guichou JF. Gelin M, et al. Among authors: labesse g. Acta Crystallogr D Biol Crystallogr. 2015 Aug;71(Pt 8):1777-87. doi: 10.1107/S1399004715010342. Epub 2015 Jul 31. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26249358

7

Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity.

Loeuillet C, Touquet B, Oury B, Eddaikra N, Pons JL, Guichou JF, Labesse G, Sereno D. Loeuillet C, et al. Among authors: labesse g. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):59-66. doi: 10.1016/j.ijpddr.2018.01.002. Epub 2018 Jan 31. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29414107 Free PMC article.

8

A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasma and Anti-Plasmodium Activities Controls Acute and Chronic Toxoplasma Infection in Mice.

Jublot D, Cavaillès P, Kamche S, Francisco D, Fontinha D, Prudêncio M, Guichou JF, Labesse G, Sereno D, Loeuillet C. Jublot D, et al. Among authors: labesse g. Int J Mol Sci. 2022 Mar 17;23(6):3254. doi: 10.3390/ijms23063254. Int J Mol Sci. 2022. PMID: 35328672 Free PMC article.

9

@TOME 3.0: Interfacing Protein Structure Modeling and Ligand Docking.

Pons JL, Reys V, Grand F, Moreau V, Gracy J, Exner TE, Labesse G. Pons JL, et al. Among authors: labesse g. J Mol Biol. 2024 Sep 1;436(17):168704. doi: 10.1016/j.jmb.2024.168704. Epub 2024 Jul 22. J Mol Biol. 2024. PMID: 39237192 Free article.

10

Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors.

Yang Y, Padilla A, Zhang C, Labesse G, Kaminski PA. Yang Y, et al. Among authors: labesse g. J Mol Biol. 2009 Dec 4;394(3):435-47. doi: 10.1016/j.jmb.2009.10.004. Epub 2009 Oct 12. J Mol Biol. 2009. PMID: 19822152

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