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Page 1
Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.
Velcicky J, Mathison CJN, Nikulin V, Pflieger D, Epple R, Azimioara M, Cow C, Michellys PY, Rigollier P, Beisner DR, Bodendorf U, Guerini D, Liu B, Wen B, Zaharevitz S, Brandl T. Velcicky J, et al. Among authors: brandl t. ACS Med Chem Lett. 2019 May 23;10(6):887-892. doi: 10.1021/acsmedchemlett.9b00044. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223443 Free PMC article.
Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo.
Velcicky J, Bodendorf U, Rigollier P, Epple R, Beisner DR, Guerini D, Smith P, Liu B, Feifel R, Wipfli P, Aichholz R, Couttet P, Dix I, Widmer T, Wen B, Brandl T. Velcicky J, et al. Among authors: brandl t. J Med Chem. 2018 Feb 8;61(3):865-880. doi: 10.1021/acs.jmedchem.7b01371. Epub 2018 Jan 23. J Med Chem. 2018. PMID: 29359565
Trypsin inhibitors for the treatment of pancreatitis.
Brandl T, Simic O, Skaanderup PR, Namoto K, Berst F, Ehrhardt C, Schiering N, Mueller I, Woelcke J. Brandl T, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4340-4. doi: 10.1016/j.bmcl.2016.07.029. Epub 2016 Jul 17. Bioorg Med Chem Lett. 2016. PMID: 27476144
Influence of Peripheral Alkyl Groups on Junction Configurations in Single-Molecule Electronics.
Ornago L, Zwick P, van der Poel S, Brandl T, El Abbassi M, Perrin ML, Dulić D, van der Zant HSJ, Mayor M. Ornago L, et al. Among authors: brandl t. J Phys Chem C Nanomater Interfaces. 2024 Jan 16;128(3):1413-1422. doi: 10.1021/acs.jpcc.3c06970. eCollection 2024 Jan 25. J Phys Chem C Nanomater Interfaces. 2024. PMID: 38293692 Free PMC article.
Iron in a Cage: Fixation of a Fe(II)tpy2 Complex by Fourfold Interlinking.
Brandl T, Johannsen S, Häussinger D, Suryadevara N, Prescimone A, Bernhard S, Gruber M, Ruben M, Berndt R, Mayor M. Brandl T, et al. Angew Chem Int Ed Engl. 2020 Sep 7;59(37):15947-15952. doi: 10.1002/anie.202006340. Epub 2020 Jun 29. Angew Chem Int Ed Engl. 2020. PMID: 32412664 Free PMC article.
20 results