Kalbacher H - Search Results

1

Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors.

Bitschar K, Sauer B, Focken J, Dehmer H, Moos S, Konnerth M, Schilling NA, Grond S, Kalbacher H, Kurschus FC, Götz F, Krismer B, Peschel A, Schittek B. Bitschar K, et al. Among authors: kalbacher h. Nat Commun. 2019 Jun 21;10(1):2730. doi: 10.1038/s41467-019-10646-7. Nat Commun. 2019. PMID: 31227691 Free PMC article.

2

Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B. Zipperer A, et al. Among authors: kalbacher h. Nature. 2016 Jul 28;535(7613):511-6. doi: 10.1038/nature18634. Nature. 2016. PMID: 27466123

3

Synthetic Lugdunin Analogues Reveal Essential Structural Motifs for Antimicrobial Action and Proton Translocation Capability.

Schilling NA, Berscheid A, Schumacher J, Saur JS, Konnerth MC, Wirtz SN, Beltrán-Beleña JM, Zipperer A, Krismer B, Peschel A, Kalbacher H, Brötz-Oesterhelt H, Steinem C, Grond S. Schilling NA, et al. Among authors: kalbacher h. Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9234-9238. doi: 10.1002/anie.201901589. Epub 2019 May 27. Angew Chem Int Ed Engl. 2019. PMID: 31059155 Free PMC article.

4

Dermcidin-derived peptides show a different mode of action than the cathelicidin LL-37 against Staphylococcus aureus.

Senyürek I, Paulmann M, Sinnberg T, Kalbacher H, Deeg M, Gutsmann T, Hermes M, Kohler T, Götz F, Wolz C, Peschel A, Schittek B. Senyürek I, et al. Among authors: kalbacher h. Antimicrob Agents Chemother. 2009 Jun;53(6):2499-509. doi: 10.1128/AAC.01679-08. Epub 2009 Apr 13. Antimicrob Agents Chemother. 2009. PMID: 19364862 Free PMC article.

5

Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo.

Rieg S, Steffen H, Seeber S, Humeny A, Kalbacher H, Dietz K, Garbe C, Schittek B. Rieg S, et al. Among authors: kalbacher h. J Immunol. 2005 Jun 15;174(12):8003-10. doi: 10.4049/jimmunol.174.12.8003. J Immunol. 2005. PMID: 15944307

6

Dermcidin: a novel human antibiotic peptide secreted by sweat glands.

Schittek B, Hipfel R, Sauer B, Bauer J, Kalbacher H, Stevanovic S, Schirle M, Schroeder K, Blin N, Meier F, Rassner G, Garbe C. Schittek B, et al. Among authors: kalbacher h. Nat Immunol. 2001 Dec;2(12):1133-7. doi: 10.1038/ni732. Nat Immunol. 2001. PMID: 11694882

7

Naturally processed dermcidin-derived peptides do not permeabilize bacterial membranes and kill microorganisms irrespective of their charge.

Steffen H, Rieg S, Wiedemann I, Kalbacher H, Deeg M, Sahl HG, Peschel A, Götz F, Garbe C, Schittek B. Steffen H, et al. Among authors: kalbacher h. Antimicrob Agents Chemother. 2006 Aug;50(8):2608-20. doi: 10.1128/AAC.00181-06. Antimicrob Agents Chemother. 2006. PMID: 16870749 Free PMC article.

8

Resistance to dermcidin-derived peptides is independent of bacterial protease activity.

Senyürek I, Döring G, Kalbacher H, Deeg M, Peschel A, Wolz C, Schittek B. Senyürek I, et al. Among authors: kalbacher h. Int J Antimicrob Agents. 2009 Jul;34(1):86-90. doi: 10.1016/j.ijantimicag.2008.12.008. Epub 2009 Feb 7. Int J Antimicrob Agents. 2009. PMID: 19201578

9

Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions.

Rieg S, Garbe C, Sauer B, Kalbacher H, Schittek B. Rieg S, et al. Among authors: kalbacher h. Br J Dermatol. 2004 Sep;151(3):534-9. doi: 10.1111/j.1365-2133.2004.06081.x. Br J Dermatol. 2004. PMID: 15377337

10

The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion.

Ernst CM, Staubitz P, Mishra NN, Yang SJ, Hornig G, Kalbacher H, Bayer AS, Kraus D, Peschel A. Ernst CM, et al. Among authors: kalbacher h. PLoS Pathog. 2009 Nov;5(11):e1000660. doi: 10.1371/journal.ppat.1000660. Epub 2009 Nov 13. PLoS Pathog. 2009. PMID: 19915718 Free PMC article.

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