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Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control.
Sanseviero E, O'Brien EM, Karras JR, Shabaneh TB, Aksoy BA, Xu W, Zheng C, Yin X, Xu X, Karakousis GC, Amaravadi RK, Nam B, Turk MJ, Hammerbacher J, Rubinstein MP, Schuchter LM, Mitchell TC, Liu Q, Stone EL. Sanseviero E, et al. Among authors: rubinstein mp. Cancer Immunol Res. 2019 Aug;7(8):1371-1380. doi: 10.1158/2326-6066.CIR-18-0386. Epub 2019 Jun 25. Cancer Immunol Res. 2019. PMID: 31239316 Free PMC article.
Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
Doedens AL, Rubinstein MP, Gross ET, Best JA, Craig DH, Baker MK, Cole DJ, Bui JD, Goldrath AW. Doedens AL, et al. Among authors: rubinstein mp. Cancer Immunol Res. 2016 Sep 2;4(9):799-811. doi: 10.1158/2326-6066.CIR-15-0178. Epub 2016 Aug 2. Cancer Immunol Res. 2016. PMID: 27485135 Free PMC article.
Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Johnson CB, May BR, Riesenberg BP, Suriano S, Mehrotra S, Garrett-Mayer E, Salem ML, Jeng EK, Wong HC, Paulos CM, Wrangle JM, Cole DJ, Rubinstein MP. Johnson CB, et al. Among authors: rubinstein mp. Cancer Res. 2018 Jun 1;78(11):3067-3074. doi: 10.1158/0008-5472.CAN-17-2153. Epub 2018 Apr 10. Cancer Res. 2018. PMID: 29636345 Free PMC article.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Rubinstein MP, et al. Cancer Immunol Immunother. 2015 May;64(5):539-49. doi: 10.1007/s00262-015-1655-y. Epub 2015 Feb 13. Cancer Immunol Immunother. 2015. PMID: 25676709 Free PMC article.
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Neitzke DJ, Bowers JS, Andrijauskaite K, O'Connell NS, Garrett-Mayer E, Wrangle J, Li Z, Paulos CM, Cole DJ, Rubinstein MP. Neitzke DJ, et al. Among authors: rubinstein mp. Cancer Immunol Immunother. 2017 Jun;66(6):737-751. doi: 10.1007/s00262-017-1965-3. Epub 2017 Mar 9. Cancer Immunol Immunother. 2017. PMID: 28280853 Free PMC article.
Lack of p53 Augments Antitumor Functions in Cytolytic T Cells.
Banerjee A, Thyagarajan K, Chatterjee S, Chakraborty P, Kesarwani P, Soloshchenko M, Al-Hommrani M, Andrijauskaite K, Moxley K, Janakiraman H, Scheffel MJ, Helke K, Armenson K, Palanisamy V, Rubinstein MP, Mayer EG, Cole DJ, Paulos CM, Christina-Voelkel-Johnson, Nishimura MI, Mehrotra S. Banerjee A, et al. Among authors: rubinstein mp. Cancer Res. 2016 Sep 15;76(18):5229-5240. doi: 10.1158/0008-5472.CAN-15-1798. Epub 2016 Jul 27. Cancer Res. 2016. PMID: 27466285 Free PMC article.
IL-2 and Beyond in Cancer Immunotherapy.
Wrangle JM, Patterson A, Johnson CB, Neitzke DJ, Mehrotra S, Denlinger CE, Paulos CM, Li Z, Cole DJ, Rubinstein MP. Wrangle JM, et al. Among authors: rubinstein mp. J Interferon Cytokine Res. 2018 Feb;38(2):45-68. doi: 10.1089/jir.2017.0101. J Interferon Cytokine Res. 2018. PMID: 29443657 Free PMC article. Review.
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines.
Dwyer CJ, Knochelmann HM, Smith AS, Wyatt MM, Rangel Rivera GO, Arhontoulis DC, Bartee E, Li Z, Rubinstein MP, Paulos CM. Dwyer CJ, et al. Among authors: rubinstein mp. Front Immunol. 2019 Feb 20;10:263. doi: 10.3389/fimmu.2019.00263. eCollection 2019. Front Immunol. 2019. PMID: 30842774 Free PMC article. Review.
102 results