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Correction: S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells.
Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Vrzalikova K, et al. Among authors: spiegel s. Leukemia. 2019 Aug;33(8):2126. doi: 10.1038/s41375-019-0511-z. Leukemia. 2019. PMID: 31239494 Free PMC article.
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, Spiegel S. Hait NC, et al. Among authors: spiegel s. Science. 2009 Sep 4;325(5945):1254-7. doi: 10.1126/science.1176709. Science. 2009. PMID: 19729656 Free PMC article.
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S. Lépine S, et al. Among authors: spiegel s. J Biol Chem. 2011 Dec 30;286(52):44380-90. doi: 10.1074/jbc.M111.257519. Epub 2011 Nov 3. J Biol Chem. 2011. PMID: 22052905 Free PMC article.
Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulum stress-induced autophagy (Lepine, S., Allegood, J. C., Park, M., Dent, P., Milstien, S., and Spiegel, S. (2011 …
Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulu …
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma.
Price MM, Oskeritzian CA, Falanga YT, Harikumar KB, Allegood JC, Alvarez SE, Conrad D, Ryan JJ, Milstien S, Spiegel S. Price MM, et al. Among authors: spiegel s. J Allergy Clin Immunol. 2013 Feb;131(2):501-11.e1. doi: 10.1016/j.jaci.2012.07.014. Epub 2012 Aug 30. J Allergy Clin Immunol. 2013. PMID: 22939756 Free PMC article.
498 results