Beachy PA - Search Results

1

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.

Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A. Deshpande I, et al. Among authors: beachy pa. Nature. 2019 Jul;571(7764):284-288. doi: 10.1038/s41586-019-1355-4. Epub 2019 Jul 1. Nature. 2019. PMID: 31263273 Free PMC article.

2

A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.

Hall TM, Porter JA, Beachy PA, Leahy DJ. Hall TM, et al. Among authors: beachy pa. Nature. 1995 Nov 9;378(6553):212-6. doi: 10.1038/378212a0. Nature. 1995. PMID: 7477329

3

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA. Porter JA, et al. Among authors: beachy pa. Nature. 1995 Mar 23;374(6520):363-6. doi: 10.1038/374363a0. Nature. 1995. PMID: 7885476

4

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.

Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA. Taipale J, et al. Among authors: beachy pa. Nature. 2000 Aug 31;406(6799):1005-9. doi: 10.1038/35023008. Nature. 2000. PMID: 10984056

5

The Hedgehog and Wnt signalling pathways in cancer.

Taipale J, Beachy PA. Taipale J, et al. Among authors: beachy pa. Nature. 2001 May 17;411(6835):349-54. doi: 10.1038/35077219. Nature. 2001. PMID: 11357142 Review.

6

Patched acts catalytically to suppress the activity of Smoothened.

Taipale J, Cooper MK, Maiti T, Beachy PA. Taipale J, et al. Among authors: beachy pa. Nature. 2002 Aug 22;418(6900):892-7. doi: 10.1038/nature00989. Nature. 2002. PMID: 12192414

7

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.

Cooper MK, Wassif CA, Krakowiak PA, Taipale J, Gong R, Kelley RI, Porter FD, Beachy PA. Cooper MK, et al. Among authors: beachy pa. Nat Genet. 2003 Apr;33(4):508-13. doi: 10.1038/ng1134. Epub 2003 Mar 24. Nat Genet. 2003. PMID: 12652302

8

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.

Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA. Berman DM, et al. Among authors: beachy pa. Nature. 2003 Oct 23;425(6960):846-51. doi: 10.1038/nature01972. Epub 2003 Sep 14. Nature. 2003. PMID: 14520411

9

Hedgehog signalling in prostate regeneration, neoplasia and metastasis.

Karhadkar SS, Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA. Karhadkar SS, et al. Among authors: beachy pa. Nature. 2004 Oct 7;431(7009):707-12. doi: 10.1038/nature02962. Epub 2004 Sep 12. Nature. 2004. PMID: 15361885

10

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.

McLellan JS, Zheng X, Hauk G, Ghirlando R, Beachy PA, Leahy DJ. McLellan JS, et al. Among authors: beachy pa. Nature. 2008 Oct 16;455(7215):979-83. doi: 10.1038/nature07358. Epub 2008 Sep 14. Nature. 2008. PMID: 18794898 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

141 results

Search Page

Filters