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Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group.
Bhojwani D, Burke MJ, Horton T, Ziegler DS, Sulis ML, Schultz KR, Wayne A, Izraeli S, Chang BH. Bhojwani D, et al. Among authors: horton t. Pediatr Hematol Oncol. 2017 Sep-Oct;34(6-7):355-364. doi: 10.1080/08880018.2017.1395937. Epub 2017 Nov 30. Pediatr Hematol Oncol. 2017. PMID: 29190164 Free PMC article.
The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.
Mirali S, Botham A, Voisin V, Xu C, St-Germain J, Sharon D, Hoff FW, Qiu Y, Hurren R, Gronda M, Jitkova Y, Nachmias B, MacLean N, Wang X, Arruda A, Minden MD, Horton TM, Kornblau SM, Chan SM, Bader GD, Raught B, Schimmer AD. Mirali S, et al. Sci Transl Med. 2020 Apr 8;12(538):eaaz8264. doi: 10.1126/scitranslmed.aaz8264. Sci Transl Med. 2020. PMID: 32269163
Tumor-associated myeloid cells provide critical support for T-ALL.
Lyu A, Triplett TA, Nam SH, Hu Z, Arasappan D, Godfrey WH, Ames RY, Sarang A, Selden HJ, Lee CH, Georgiou G, Horton TM, Ehrlich LIR. Lyu A, et al. Blood. 2020 Oct 15;136(16):1837-1850. doi: 10.1182/blood.2020007145. Blood. 2020. PMID: 32845007 Free article.
Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors.
Franke NE, Kaspers GL, Assaraf YG, van Meerloo J, Niewerth D, Kessler FL, Poddighe PJ, Kole J, Smeets SJ, Ylstra B, Bi C, Chng WJ, Horton TM, Menezes RX, Musters RJ, Zweegman S, Jansen G, Cloos J. Franke NE, et al. Oncotarget. 2016 Nov 15;7(46):74779-74796. doi: 10.18632/oncotarget.11340. Oncotarget. 2016. PMID: 27542283 Free PMC article.
366 results