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Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
Gali CC, Fanaee-Danesh E, Zandl-Lang M, Albrecher NM, Tam-Amersdorfer C, Stracke A, Sachdev V, Reichmann F, Sun Y, Avdili A, Reiter M, Kratky D, Holzer P, Lass A, Kandimalla KK, Panzenboeck U. Gali CC, et al. Among authors: kandimalla kk. Mol Cell Neurosci. 2019 Sep;99:103390. doi: 10.1016/j.mcn.2019.103390. Epub 2019 Jul 2. Mol Cell Neurosci. 2019. PMID: 31276749 Free PMC article.
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