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MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma.
Vella S, Pomella S, Leoncini PP, Colletti M, Conti B, Marquez VE, Strillacci A, Roma J, Gallego S, Milano GM, Capogrossi MC, Bertaina A, Ciarapica R, Rota R. Vella S, et al. Among authors: pomella s. Clin Epigenetics. 2015 Aug 6;7(1):82. doi: 10.1186/s13148-015-0107-z. eCollection 2015. Clin Epigenetics. 2015. PMID: 26251675 Free PMC article.
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.
Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song Y, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer M, Shern JF, Zhao K, Thomas CJ, Khan J. Gryder BE, et al. Among authors: pomella s. Cancer Discov. 2017 Aug;7(8):884-899. doi: 10.1158/2159-8290.CD-16-1297. Epub 2017 Apr 26. Cancer Discov. 2017. PMID: 28446439 Free PMC article.
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma.
Gryder BE, Pomella S, Sayers C, Wu XS, Song Y, Chiarella AM, Bagchi S, Chou HC, Sinniah RS, Walton A, Wen X, Rota R, Hathaway NA, Zhao K, Chen J, Vakoc CR, Shern JF, Stanton BZ, Khan J. Gryder BE, et al. Among authors: pomella s. Nat Genet. 2019 Dec;51(12):1714-1722. doi: 10.1038/s41588-019-0534-4. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784732 Free PMC article.
Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage.
Gryder BE, Wachtel M, Chang K, El Demerdash O, Aboreden NG, Mohammed W, Ewert W, Pomella S, Rota R, Wei JS, Song Y, Stanton BZ, Schäfer B, Vakoc CR, Khan J. Gryder BE, et al. Among authors: pomella s. iScience. 2020 May 22;23(5):101103. doi: 10.1016/j.isci.2020.101103. Epub 2020 Apr 29. iScience. 2020. PMID: 32416589 Free PMC article.
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
Romanelli A, Stazi G, Fioravanti R, Zwergel C, Di Bello E, Pomella S, Perrone C, Battistelli C, Strippoli R, Tripodi M, Del Bufalo D, Rota R, Trisciuoglio D, Mai A, Valente S. Romanelli A, et al. Among authors: pomella s. ACS Med Chem Lett. 2020 Mar 19;11(5):977-983. doi: 10.1021/acsmedchemlett.0c00014. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435414 Free PMC article.
FAK Signaling in Rhabdomyosarcoma.
Perrone C, Pomella S, Cassandri M, Braghini MR, Pezzella M, Locatelli F, Rota R. Perrone C, et al. Among authors: pomella s. Int J Mol Sci. 2020 Nov 10;21(22):8422. doi: 10.3390/ijms21228422. Int J Mol Sci. 2020. PMID: 33182556 Free PMC article. Review.
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