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Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.
Di WL, Lwin SM, Petrova A, Bernadis C, Syed F, Farzaneh F, Moulding D, Martinez AE, Sebire NJ, Rampling D, Virasami A, Zamiri M, Wang W, Hara H, Kadiyirire T, Abdul-Wahab A, Martinez-Queipo M, Harper JI, McGrath JA, Thrasher AJ, Mellerio JE, Qasim W. Di WL, et al. Among authors: hara h. Hum Gene Ther. 2019 Sep;30(9):1067-1078. doi: 10.1089/hum.2019.049. Epub 2019 Aug 5. Hum Gene Ther. 2019. PMID: 31288584 Clinical Trial.
Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
Morris EC, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, Grace S, Gilmour K, Workman S, Buckland K, Butler K, Chee R, Salama AD, Ibrahim H, Hara H, Duret C, Mavilio F, Male F, Bushman FD, Galy A, Burns SO, Gaspar HB, Thrasher AJ. Morris EC, et al. Among authors: hara h. Blood. 2017 Sep 14;130(11):1327-1335. doi: 10.1182/blood-2017-04-777136. Epub 2017 Jul 17. Blood. 2017. PMID: 28716862 Free PMC article.
Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome.
Hacein-Bey Abina S, Gaspar HB, Blondeau J, Caccavelli L, Charrier S, Buckland K, Picard C, Six E, Himoudi N, Gilmour K, McNicol AM, Hara H, Xu-Bayford J, Rivat C, Touzot F, Mavilio F, Lim A, Treluyer JM, Héritier S, Lefrère F, Magalon J, Pengue-Koyi I, Honnet G, Blanche S, Sherman EA, Male F, Berry C, Malani N, Bushman FD, Fischer A, Thrasher AJ, Galy A, Cavazzana M. Hacein-Bey Abina S, et al. Among authors: hara h. JAMA. 2015 Apr 21;313(15):1550-63. doi: 10.1001/jama.2015.3253. JAMA. 2015. PMID: 25898053 Free PMC article. Clinical Trial.
Silicone oil, an intraocular surgical adjuvant, induces retinal ferroptosis.
Shimizu H, Tanaka H, Tazaki A, Yamada K, Suzumura A, Ota J, Ushio-Watanabe N, Zheng H, Kataoka K, Hara H, Nishikawa Y, Yasukawa T, Suzuma K, Terasaki H, Nishiguchi KM, Kato M, Toyokuni S, Kaneko H. Shimizu H, et al. Among authors: hara h. Free Radic Biol Med. 2024 Dec 18;228:33-43. doi: 10.1016/j.freeradbiomed.2024.12.039. Online ahead of print. Free Radic Biol Med. 2024. PMID: 39706501 Free article.
SPRR1A is a potential therapeutic target for osteosarcoma: in vitro and in vivo evaluations using generated artificial osteosarcoma cancer stem cell‑like cells.
Miyamoto T, Fukase N, Kawamoto T, Fujiwara S, Hara H, Sawada R, Nakamatsu Y, Mifune Y, Kakutani K, Hoshino Y, Hayashi S, Matsumoto T, Matsushita T, Koyanagi-Aoi M, Aoi T, Takemori T, Yahiro S, Kuroda R, Akisue T. Miyamoto T, et al. Among authors: hara h. Oncol Rep. 2025 Feb;53(2):24. doi: 10.3892/or.2024.8857. Epub 2024 Dec 20. Oncol Rep. 2025. PMID: 39704263 Free PMC article.
Potential of boron neutron capture therapy (BNCT) for myxofibrosarcoma.
Fujimoto T, Andoh T, Sudo T, Fujita I, Sakurai Y, Takata T, Tanaka H, Kawamoto T, Yahiro S, Nakamura S, Hara H, Fukase N, Akisue T, Ichikawa H, Kuroda R, Suzuki M. Fujimoto T, et al. Among authors: hara h. Appl Radiat Isot. 2024 Nov 26;217:111603. doi: 10.1016/j.apradiso.2024.111603. Online ahead of print. Appl Radiat Isot. 2024. PMID: 39632319
3,786 results