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Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
López-Posadas R, Fastancz P, Martínez-Sánchez LDC, Panteleev-Ivlev J, Thonn V, Kisseleva T, Becker LS, Schulz-Kuhnt A, Zundler S, Wirtz S, Atreya R, Carlé B, Friedrich O, Schürmann S, Waldner MJ, Neufert C, Brakebusch CH, Bergö MO, Neurath MF, Atreya I. López-Posadas R, et al. Among authors: neurath mf. Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11. Gastroenterology. 2019. PMID: 31302143 Free article.
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.
Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF. Tiede I, et al. Among authors: neurath mf. J Clin Invest. 2003 Apr;111(8):1133-45. doi: 10.1172/JCI16432. J Clin Invest. 2003. PMID: 12697733 Free PMC article.
Illuminating the role of type I IFNs in colitis.
Wirtz S, Neurath MF. Wirtz S, et al. Among authors: neurath mf. J Clin Invest. 2005 Mar;115(3):586-8. doi: 10.1172/JCI24518. J Clin Invest. 2005. PMID: 15765141 Free PMC article.
948 results