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Antimalarial activity of primaquine operates via a two-step biochemical relay.
Camarda G, Jirawatcharadech P, Priestley RS, Saif A, March S, Wong MHL, Leung S, Miller AB, Baker DA, Alano P, Paine MJI, Bhatia SN, O'Neill PM, Ward SA, Biagini GA. Camarda G, et al. Among authors: baker da. Nat Commun. 2019 Jul 19;10(1):3226. doi: 10.1038/s41467-019-11239-0. Nat Commun. 2019. PMID: 31324806 Free PMC article.
A transcriptional switch underlies commitment to sexual development in malaria parasites.
Kafsack BF, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás M. Kafsack BF, et al. Among authors: baker da. Nature. 2014 Mar 13;507(7491):248-52. doi: 10.1038/nature12920. Epub 2014 Feb 23. Nature. 2014. PMID: 24572369 Free PMC article.
Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines.
Campino S, Benavente ED, Assefa S, Thompson E, Drought LG, Taylor CJ, Gorvett Z, Carret CK, Flueck C, Ivens AC, Kwiatkowski DP, Alano P, Baker DA, Clark TG. Campino S, et al. Among authors: baker da. Malar J. 2016 Apr 21;15:229. doi: 10.1186/s12936-016-1254-1. Malar J. 2016. PMID: 27098483 Free PMC article.
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.
Baker DA, Stewart LB, Large JM, Bowyer PW, Ansell KH, Jiménez-Díaz MB, El Bakkouri M, Birchall K, Dechering KJ, Bouloc NS, Coombs PJ, Whalley D, Harding DJ, Smiljanic-Hurley E, Wheldon MC, Walker EM, Dessens JT, Lafuente MJ, Sanz LM, Gamo FJ, Ferrer SB, Hui R, Bousema T, Angulo-Barturén I, Merritt AT, Croft SL, Gutteridge WE, Kettleborough CA, Osborne SA. Baker DA, et al. Nat Commun. 2017 Sep 5;8(1):430. doi: 10.1038/s41467-017-00572-x. Nat Commun. 2017. PMID: 28874661 Free PMC article.
Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites.
Meerstein-Kessel L, van der Lee R, Stone W, Lanke K, Baker DA, Alano P, Silvestrini F, Janse CJ, Khan SM, van de Vegte-Bolmer M, Graumans W, Siebelink-Stoter R, Kooij TWA, Marti M, Drakeley C, Campo JJ, van Dam TJP, Sauerwein R, Bousema T, Huynen MA. Meerstein-Kessel L, et al. Among authors: baker da. Sci Rep. 2018 Jan 11;8(1):410. doi: 10.1038/s41598-017-18840-7. Sci Rep. 2018. PMID: 29323249 Free PMC article.
Signalling in malaria parasites. The MALSIG consortium.
Doerig C, Baker D, Billker O, Blackman MJ, Chitnis C, Dhar Kumar S, Heussler V, Holder AA, Kocken C, Krishna S, Langsley G, Lasonder E, Menard R, Meissner M, Pradel G, Ranford-Cartwright L, Sharma A, Sharma P, Tardieux T, Tatu U, Alano P. Doerig C, et al. Parasite. 2009 Sep;16(3):169-82. doi: 10.1051/parasite/2009163169. Parasite. 2009. PMID: 19839262 Free article. Review.
396 results