Erwood S - Search Results

1

A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene.

Kemaladewi DU, Bassi PS, Erwood S, Al-Basha D, Gawlik KI, Lindsay K, Hyatt E, Kember R, Place KM, Marks RM, Durbeej M, Prescott SA, Ivakine EA, Cohn RD. Kemaladewi DU, et al. Among authors: erwood s. Nature. 2019 Aug;572(7767):125-130. doi: 10.1038/s41586-019-1430-x. Epub 2019 Jul 24. Nature. 2019. PMID: 31341277

2

Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing.

Garcia B, Lee J, Edraki A, Hidalgo-Reyes Y, Erwood S, Mir A, Trost CN, Seroussi U, Stanley SY, Cohn RD, Claycomb JM, Sontheimer EJ, Maxwell KL, Davidson AR. Garcia B, et al. Among authors: erwood s. Cell Rep. 2019 Nov 12;29(7):1739-1746.e5. doi: 10.1016/j.celrep.2019.10.017. Cell Rep. 2019. PMID: 31722192 Free PMC article.

3

Modeling Niemann-Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation.

Erwood S, Brewer RA, Bily TMI, Maino E, Zhou L, Cohn RD, Ivakine EA. Erwood S, et al. Genome Res. 2019 Dec;29(12):2010-2019. doi: 10.1101/gr.250720.119. Epub 2019 Nov 21. Genome Res. 2019. PMID: 31754021 Free PMC article.

4

Allele-Specific Prevention of Nonsense-Mediated Decay in Cystic Fibrosis Using Homology-Independent Genome Editing.

Erwood S, Laselva O, Bily TMI, Brewer RA, Rutherford AH, Bear CE, Ivakine EA. Erwood S, et al. Mol Ther Methods Clin Dev. 2020 May 12;17:1118-1128. doi: 10.1016/j.omtm.2020.05.002. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32490033 Free PMC article.

5

STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses.

Scott O, Lindsay K, Erwood S, Mollica A, Roifman CM, Cohn RD, Ivakine EA. Scott O, et al. Among authors: erwood s. NPJ Genom Med. 2021 May 14;6(1):34. doi: 10.1038/s41525-021-00196-7. NPJ Genom Med. 2021. PMID: 33990617 Free PMC article.

6

Saturation variant interpretation using CRISPR prime editing.

Erwood S, Bily TMI, Lequyer J, Yan J, Gulati N, Brewer RA, Zhou L, Pelletier L, Ivakine EA, Cohn RD. Erwood S, et al. Nat Biotechnol. 2022 Jun;40(6):885-895. doi: 10.1038/s41587-021-01201-1. Epub 2022 Feb 21. Nat Biotechnol. 2022. PMID: 35190686

7

Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease.

Schultz ML, Schache KJ, Azaria RD, Kuiper EQ, Erwood S, Ivakine EA, Farhat NY, Porter FD, Pathmasiri KC, Cologna SM, Uhler MD, Lieberman AP. Schultz ML, et al. Among authors: erwood s. JCI Insight. 2022 Dec 8;7(23):e160308. doi: 10.1172/jci.insight.160308. JCI Insight. 2022. PMID: 36301667 Free PMC article.

8

Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What's Next.

Erwood S, Gu B. Erwood S, et al. Genes (Basel). 2020 Jan 29;11(2):140. doi: 10.3390/genes11020140. Genes (Basel). 2020. PMID: 32013077 Free PMC article. Review.

9

Activity of lumacaftor is not conserved in zebrafish Cftr bearing the major cystic fibrosis-causing mutation.

Laselva O, Erwood S, Du K, Ivakine Z, Bear CE. Laselva O, et al. Among authors: erwood s. FASEB Bioadv. 2019 Sep 18;1(10):661-670. doi: 10.1096/fba.2019-00039. eCollection 2019 Oct. FASEB Bioadv. 2019. PMID: 32123813 Free PMC article.

10

Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFβ signaling.

Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND. Rowan CJ, et al. Among authors: erwood s. Development. 2018 Jul 9;145(13):dev159947. doi: 10.1242/dev.159947. Development. 2018. PMID: 29945868

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