Darling DS - Search Results

1

ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells.

de Barrios O, Sanchez-Moral L, Cortés M, Ninfali C, Profitós-Pelejà N, Martínez-Campanario MC, Siles L, Del Campo R, Fernández-Aceñero MJ, Darling DS, Castells A, Maurel J, Salas A, Dean DC, Postigo A. de Barrios O, et al. Among authors: darling ds. Gut. 2019 Dec;68(12):2129-2141. doi: 10.1136/gutjnl-2018-317294. Epub 2019 Jul 31. Gut. 2019. PMID: 31366457

2

ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.

Sánchez-Tilló E, de Barrios O, Siles L, Amendola PG, Darling DS, Cuatrecasas M, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: darling ds. Clin Cancer Res. 2013 Mar 1;19(5):1071-82. doi: 10.1158/1078-0432.CCR-12-2675. Epub 2013 Jan 22. Clin Cancer Res. 2013. PMID: 23340304

3

ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

de Barrios O, Győrffy B, Fernández-Aceñero MJ, Sánchez-Tilló E, Sánchez-Moral L, Siles L, Esteve-Arenys A, Roué G, Casal JI, Darling DS, Castells A, Postigo A. de Barrios O, et al. Among authors: darling ds. Gut. 2017 Apr;66(4):666-682. doi: 10.1136/gutjnl-2015-310838. Epub 2016 Dec 13. Gut. 2017. PMID: 27965283

4

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles.

Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A. Cortés M, et al. Among authors: darling ds. EMBO J. 2017 Nov 15;36(22):3336-3355. doi: 10.15252/embj.201797345. Epub 2017 Oct 16. EMBO J. 2017. PMID: 29038174 Free PMC article.

5

Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3.

Ninfali C, Siles L, Darling DS, Postigo A. Ninfali C, et al. Among authors: darling ds. Nucleic Acids Res. 2018 Nov 16;46(20):10697-10708. doi: 10.1093/nar/gky835. Nucleic Acids Res. 2018. PMID: 30304480 Free PMC article.

6

ZEB1 protects skeletal muscle from damage and is required for its regeneration.

Siles L, Ninfali C, Cortés M, Darling DS, Postigo A. Siles L, et al. Among authors: darling ds. Nat Commun. 2019 Mar 25;10(1):1364. doi: 10.1038/s41467-019-08983-8. Nat Commun. 2019. PMID: 30910999 Free PMC article.

7

ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression.

Sánchez-Tilló E, de Barrios O, Valls E, Darling DS, Castells A, Postigo A. Sánchez-Tilló E, et al. Among authors: darling ds. Oncogene. 2015 Nov 12;34(46):5760-70. doi: 10.1038/onc.2015.352. Epub 2015 Sep 21. Oncogene. 2015. PMID: 26387539

8

Zeb1 links epithelial-mesenchymal transition and cellular senescence.

Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC. Liu Y, et al. Among authors: darling ds. Development. 2008 Feb;135(3):579-88. doi: 10.1242/dev.007047. Development. 2008. PMID: 18192284 Free PMC article.

9

Zeb1 mutant mice as a model of posterior corneal dystrophy.

Liu Y, Peng X, Tan J, Darling DS, Kaplan HJ, Dean DC. Liu Y, et al. Among authors: darling ds. Invest Ophthalmol Vis Sci. 2008 May;49(5):1843-9. doi: 10.1167/iovs.07-0789. Invest Ophthalmol Vis Sci. 2008. PMID: 18436818 Free PMC article.

10

Zeb1 represses Mitf and regulates pigment synthesis, cell proliferation, and epithelial morphology.

Liu Y, Ye F, Li Q, Tamiya S, Darling DS, Kaplan HJ, Dean DC. Liu Y, et al. Among authors: darling ds. Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5080-8. doi: 10.1167/iovs.08-2911. Epub 2009 Jun 10. Invest Ophthalmol Vis Sci. 2009. PMID: 19515996 Free PMC article.

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