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Page 1
ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells.
de Barrios O, Sanchez-Moral L, Cortés M, Ninfali C, Profitós-Pelejà N, Martínez-Campanario MC, Siles L, Del Campo R, Fernández-Aceñero MJ, Darling DS, Castells A, Maurel J, Salas A, Dean DC, Postigo A. de Barrios O, et al. Among authors: martinez campanario mc. Gut. 2019 Dec;68(12):2129-2141. doi: 10.1136/gutjnl-2018-317294. Epub 2019 Jul 31. Gut. 2019. PMID: 31366457
Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles.
Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A. Cortés M, et al. Among authors: martinez campanario mc. EMBO J. 2017 Nov 15;36(22):3336-3355. doi: 10.15252/embj.201797345. Epub 2017 Oct 16. EMBO J. 2017. PMID: 29038174 Free PMC article.
Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
Martinez-Campanario MC, Cortés M, Moreno-Lanceta A, Han L, Ninfali C, Domínguez V, Andrés-Manzano MJ, Farràs M, Esteve-Codina A, Enrich C, Díaz-Crespo FJ, Pintado B, Escolà-Gil JC, García de Frutos P, Andrés V, Melgar-Lesmes P, Postigo A. Martinez-Campanario MC, et al. Nat Commun. 2023 Dec 14;14(1):8316. doi: 10.1038/s41467-023-43896-7. Nat Commun. 2023. PMID: 38097578 Free PMC article.
Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation.
Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A. Cortés M, et al. Among authors: martinez campanario mc. Nat Commun. 2023 Nov 17;14(1):7471. doi: 10.1038/s41467-023-42277-4. Nat Commun. 2023. PMID: 37978290 Free PMC article.
The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
Ninfali C, Cortés M, Martínez-Campanario MC, Domínguez V, Han L, Tobías E, Esteve-Codina A, Enrich C, Pintado B, Garrabou G, Postigo A. Ninfali C, et al. Among authors: martinez campanario mc. Proc Natl Acad Sci U S A. 2023 Nov 14;120(46):e2301120120. doi: 10.1073/pnas.2301120120. Epub 2023 Nov 10. Proc Natl Acad Sci U S A. 2023. PMID: 37948583 Free PMC article.